Results 101 to 110 of about 14,780 (225)

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

Frontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez, Cecilia Ortíz, Estefania Dibello, Estefania Dibello, Marcelo A. Comini   +4 more
doaj   +1 more source

Trypanosoma brucei triggers a marked immune response in male reproductive organs. [PDF]

PLoS Neglected Tropical Diseases, 2018
African trypanosomiasis is caused by the protozoan parasite Trypanosoma brucei, transmitted between mammals by the bite of a tsetse. It has been recently shown that parasites accumulate in large numbers in various organs and tissues, including the mouse ...
Tânia Carvalho, Sandra Trindade, Sílvia Pimenta, Ana B Santos, Filipa Rijo-Ferreira, Luísa M Figueiredo   +5 more
doaj   +1 more source

Pandemic Prevention Paradigms: Understanding Global Health Governance

Public Health Challenges, Volume 4, Issue 2, June 2025.
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr, Cinzia Santucciu, Valentina Chisu, Narges Lotfalizadeh, Shakiba Nazemian, Negin Esfandiari, Ashkan Hajjafari, Helia Sepahvand, Abbas Rahdar, Sadanand Pandey, Hassan Borji   +10 more
wiley   +1 more source

Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]

, 2014
It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer, Agbe, Bruhn, Brun, Cristodero, Dean, Deterding, Herbert, Hoare, Holmes, Kaminsky, Lai, Lanteri, M. K. Gould, Mathis, Mukherjee, Painter, Priest, Roy Chowdhury, Räz, Schnaufer, Schnaufer, Schnaufer, Shapiro, Stuart, Tang, Thuita, Ward, Wenzler, Wenzler, Wilson, Zhang, Zuma   +32 more
core   +1 more source

Perceived Threat of Zoonotic Infections in Abattoir Workers in the Tamale Metropolis of Ghana: An Assessment of Knowledge, Attitudes and Practices

Public Health Challenges, Volume 4, Issue 2, June 2025.
Most abattoir workers (90.2%) knew that humans can get zoonotic diseases from the animals they handle. However, some respondents believe that witchcraft (20.0%), curses (20.8%) and supernatural powers (18.0%) cause zoonotic diseases. ABSTRACT Background Abattoir workers are more prone to acquiring zoonotic diseases.
Benjamin Nuhu Tingbani, Ezekiel Kofi Vicar, Stephen Apanga, Elijah Bisuman Sambian, Samuel Tamanyian Suuk, Edmond Nakinpaak Biibantib, Williams Walana   +6 more
wiley   +1 more source

Regulator experiences of trials during Ebola epidemics in Sierra Leone, Guinea, and the Democratic Republic of the Congo

Tropical Medicine &International Health, Volume 30, Issue 6, Page 539-546, June 2025.
Abstract Introduction During the 2014–2016 Ebola epidemic in West Africa and the Ebola outbreaks between 2018 and 2020 in the Democratic Republic of Congo, vaccines and other tools for prevention and treatment had to be taken through trials in exceptional circumstances using accelerated processes.
Kambale Kasonia, Frank Baiden, Frédéric Le Marcis, Bruno Lapika, Joel Kiyulu, Henri Kimina, Freddy Bikioli, Fanny Attas, Anthony Mansaray, Rose Burns, Elysée Nouvet, Séverine Thys, Antea Paviotti, Daniela Manno, Mukeh Kenneth Fahnbulleh, Bailah Leigh, Mohamed Samai, Brian Greenwood, Shelley Lees, Patrick Mitashi Mulopo, Deborah Watson‐Jones   +20 more
wiley   +1 more source

Identifying Cattle Breed-Specific Partner Choice of Transcription Factors during the African Trypanosomiasis Disease Progression Using Bioinformatics Analysis

Vaccines, 2020
African Animal Trypanosomiasis (AAT) is a disease caused by pathogenic trypanosomes which affects millions of livestock every year causing huge economic losses in agricultural production especially in sub-Saharan Africa.
Abirami Rajavel, Felix Heinrich, Armin Otto Schmitt, Mehmet Gültas   +3 more
doaj   +1 more source

Human African trypanosomiasis [PDF]

, 2009
Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies.
Abel, Agranoff, Ancelle, Ayed, Balasegaram, Balasegaram, Barrett, Barrett, Barrett, Bayer, Bedat-Millet, Bisoffi, Bisser, Bisser, Blum, Blum, Blum, Blum, Blum, Blum, Bronner, Brun, Buguet, Burri, Burri, Chappuis, Chappuis, Chappuis, Chappuis, Chappuis, Chappuis, Checchi, Checchi, Christian Burri, Courtioux, De Raadt, Deborggraeve, Deborggraeve, Dorlo, Doua, Duggan, Dukes, Ekwanzala, Enyaru, Ezzedine, Fevre, Fevre, Francois Chappuis, Greenwood, Gustafsson, Hutchinson, Iborra, Inojosa, Iten, Jamonneau, Jamonneau, Jamonneau, Jamonneau, Jamonneau, Jansson, Jelinek, Johannes Blum, Jordan, Joshi, Kabasa, Kennedy, Kennedy, Koten, Lejon, Lejon, Lejon, Lejon, Lejon, Lejon, Lejon, Lejon, Louis, Lumsden, Lundkvist, Lutumba, Lutumba, Lutumba, Lutumba, MacLean, Macleod, Magnus, Marcello, Marcello, Masocha, Maudlin, Mendonca, Moore, Moore, Moore, Na-Bangchang, Njiokou, Njiru, Noireau, Noireau, Odiit, Odiit, Oscherwitz, Papadopoulos, Paquet, Penchenier, Pepin, Picozzi, Priotto, Priotto, Priotto, Reincke, Reto Brun, Ripamonti, Robays, Robays, Ruiz, Schmid, Shiflett, Simarro, Simarro, Simarro, Simo, Smith, Spencer, Stanghellini, Stevens, Steverding, Steverding, Stijlemans, Stuart, Taylor, Torr, Truc, Truc, Truc, Truc, Van Meirvenne, Van Nieuwenhove, Vanhamme, Vanhollebeke, Vreysen, Welburn, Welburn, Woo   +143 more
core   +2 more sources

Risk Evaluation and Mitigation Strategies for Newly Detected Mysterious Dinga Dinga Virus Infection in Africa: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains ...
Sabrina Sharmin, Salsabil Islam, Md. Aminul Haque, Md. Rabiul Islam   +3 more
wiley   +1 more source

Tick Species Infesting Livestock in Three Bioclimatic Areas of Senegal: Bioecology, Prevalence of Tick Infestation, Associated Categorical Factors and Crimean‐Congo Haemorrhagic Fever Virus Infection

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Ticks were collected between October 2020 and November 2022, from cattle, goats and sheep in the Sahelian, Sudano‐Sahelian and Sudanian zones, and tested for CCHFV infection. A total of 3632 animals were examined and 35.3% (95% CI: 33.8–36.9) found tick‐infested.
Aliou Khoule, Déthié Ngom, Mouhamet Faye, Ousseynou Sene, Aminata Badji, Elhadji Ndiaye, Gamou Fall, Ibrahima Dia, Mawlouth Diallo, Diawo Diallo   +9 more
wiley   +1 more source