Results 31 to 40 of about 345,011 (254)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Historical overview of lipid biochemistry research: from initial hypotheses to understanding the biological role of N-acylethanolamines [PDF]

The Ukrainian Biochemical Journal
In the Department of Lipid Biochemistry at the Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, a systematic approach to studying the functional role of lipids and investigating the lipidome of mammals and humans was ...
H. V. Kosiakova, A. G. Berdyshev, T. M. Horidko, V. M. Klimashevsky, O. F. Meged, O. S. Tkachenko, N. L. Kindruk, O. V. Zhukov, V. S. Asmolkova, N. M. Hula   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

GLP1 and GIP are involved in the action of synbiotics in broiler chickens

Journal of Animal Science and Biotechnology, 2018
Background In order to discover new strategies to replace antibiotics in the post-antibiotic era in meat-type chicken production, two new synbiotics were tested: (Lactobacillus salivarius IBB3154 plus galactooligosaccharide (Syn1) and Lactobacillus ...
Pawel Antoni Kolodziejski, Maciej Sassek, Daniela Chalupka, Natalia Leciejewska, Leszek Nogowski, Pawel Mackowiak, Damian Jozefiak, Katarzyna Stadnicka, Maria Siwek, Marek Bednarczyk, Tomasz Szwaczkowski, Ewa Pruszynska-Oszmalek   +11 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Analysis of toxicity and anticancer activity of micelles of sodium alginate-curcumin

International Journal of Nanomedicine, 2019
Alicja Karabasz1, Dorota Lachowicz2, Anna Karewicz3, Renata Mezyk-Kopec1, Krystyna Stalińska1, Ewa Werner4,5, Agnieszka Cierniak6, Grzegorz Dyduch7, Joanna Bereta1, Monika Bzowska1 1Department of Cell Biochemistry, Faculty of Biochemistry, Biophysics and
Karabasz A, Lachowicz D, Karewicz A, Mezyk-Kopec R, Stalińska K, Werner E, Cierniak A, Dyduch G, Bereta J, Bzowska M   +9 more
doaj  

Assessing the health hazard originated via pesticide chemicals in human through rabbit model in agricultural production system in Bangladesh

BMC Pharmacology and Toxicology, 2022
Background The use of chemical pesticides in developing countries like Bangladesh and their impacts on human health and food security is a global concern. Bangladesh is an agricultural dependent country for the growing population demand for food security
Amir Hossan Shaikat, Shahneaz Ali Khan, Mohammed Ashif Imtiaz, Md Ridoan Pasha, Jabin Sultana, Arfanul Saif, Mohammad Rashedul Alam   +6 more
doaj   +1 more source

Chorioallantoic Membrane Models of Various Avian Species: Differences and Applications

Biology, 2021
The chorioallantoic membrane model (CAM) of an avian embryo is used as an experimental model in various fields of research, including angiogenesis research and drug testing, xenografting and cancer research, and other scientific and commercial ...
Barbora Kundeková, Mariana Máčajová, Majlinda Meta, Ivan Čavarga, Boris Bilčík   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Haematology and Clinical Biochemistry Findings Associated with Equine Diseases - a Review

Notulae Scientia Biologicae, 2017
The course and outcome of a disease process is dependent upon factors such as the disease-causing agent and its cell tropism, defense mechanisms of the host, genetic resistance of the species or breed affected, as well as the age, nutritional status and ...
Onyinyechukwu A. AGINA
doaj   +1 more source