Results 51 to 60 of about 352,615 (299)

Panel 4: Recent Advances in Otitis Media in Molecular Biology, Biochemistry, Genetics, and Animal Models

, 2013
Background. Otitis media (OM) is the most common childhood bacterial infection and also the leading cause of conductive hearing loss in children. Currently, there is an urgent need for developing novel therapeutic agents for treating OM based on full ...
Allen F. Ryan, Jung, Timothy T. K., Ann Hermansson, Brown, Steve D., Bakaletz, Lauren O., Post, J. Christopher, Sung‐Kyun Moon, Steven K. Juhn, Jae Hyang Lim, J. Christopher Post, Hermansson, Ann, Cheeseman, Michael T., Lim, Jae Hyang, Michael T. Cheeseman, Steve D. Brown, Jizhen Lin, David J. Lim, Juhn, Steven K., Ryan, Allen F., Lin, Jizhen, Jian‐Dong Li, Moon, Sung-Kyun, Lim, David J., Li, Jian-Dong, Lauren O. Bakaletz, Lund University., Timothy T. K. Jung, Hermansson, Ann,   +27 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Different expression of lipid metabolism-related genes in Shandong black cattle and Luxi cattle based on transcriptome analysis

Scientific Reports, 2020
To provide new ideas for improving meat quality and generating new breeds of cattle, the important candidate genes affecting fat deposition in two kinds of cattle were identified. Eighteen months Shandong black cattle (n = 3) and Luxi cattle (n = 3) were
Ruili Liu, Xianxun Liu, Xuejin Bai, Chaozhu Xiao, Yajuan Dong   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Mathematical modelling in animal nutrition: a centenary review

, 2008
A centenary review presents an opportunity to ponder over the processes of concept development and give thought to future directions. The current review aims to ascertain the ontogeny of current concepts, underline the connection between ideas and people
Dijkstra, J., Dumas, A., France, J., J. DIJKSTRA, A. DUMAS, J. FRANCE   +5 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Dietary bile acids supplementation protects against Salmonella Typhimurium infection via improving intestinal mucosal barrier and gut microbiota composition in broilers

Journal of Animal Science and Biotechnology
Background Salmonella Typhimurium (S. Typhimurium) is a common pathogenic microorganism and poses a threat to the efficiency of poultry farms. As signaling molecules regulating the interaction between the host and gut microbiota, bile acids (BAs) play a ...
Dan Hu, Xiaoran Yang, Ming Qin, Li’an Pan, Haiyan Fang, Pengnan Chen, Yingdong Ni   +6 more
doaj   +1 more source

INFLUENCE OF FEEDING ONION WASTE ON SOME BLOOD COMPONENTS AND RUMEN PARAMETERS OF SHEEP

Assiut Veterinary Medical Journal, 2009
  The effect of long term (60 days) of onion waste feeding (as economic Source of feed ) on some blood constituents and rumen parameters of 30 non pregnant balady ewes during the interval period was studied at private farm located in Manzala, Dakahlia ...
R.A. EL-RAMADY, S.A. TAWFIK, H.A. SHALABY, S.S.S. YONIS   +3 more
doaj   +1 more source

Sablefish (Anoplopoma fimbra Pallas, 1814) plasma biochemistry and hematology reference intervals including blood cell morphology.

PLoS ONE, 2021
Plasma biochemistry and hematology reference intervals are integral health assessment tools in all medical fields, including aquatic animal health.
Carla B Schubiger, M Elena Gorman, Jennifer L Johns, Mary R Arkoosh, Joseph P Dietrich   +4 more
doaj   +1 more source