Results 71 to 80 of about 2,222,991 (278)

Biochemistry Question Papers - 2015

open access: yes, 2015
Biochemistry Question Papers ...
Vidyasagar University
core   +1 more source

UHPLC/MS Profile and Antimalarial Potency of Enantia chlorantha Oliv. (Annonaceae) Stem Bark Aqueous Extract

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences
The escalating challenge of malaria management, primarily driven by antimalarial drug resistance, necessitates the urgent exploration of novel therapeutic agents.
Abel Narcisse Messi Betene   +14 more
doaj   +1 more source

Dietary Supplementation of Encapsulated Dendrophthoe pentandra Leaf Extract in Broilers under High Stocking Density

open access: yesTropical Animal Science Journal
High stocking density can compromise broiler welfare and physiological homeostasis, but the magnitude of the challenge depends on housing and environmental conditions.
E. Widiastuti   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Expression of NR3C1, INSR and SLC2A4 genes in skeletal muscles and CBG in liver depends on age and breed of pigs

open access: yesCzech Journal of Animal Science, 2019
The genes encoding glucose transporter 4 (SLC2A4, GLUT4), insulin receptor (INSR) and glucocorticoid receptor (NR3C1) are considered regulators of energy metabolism that may influence fat content in skeletal muscle at different ages and breeds of pigs ...
Dawid Szczepankiewicz   +10 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Antiosteoporotic treatment promotes tendon-to-bone healing after rotator cuff repair: a systematic review of animal studies

open access: yesBone & Joint Research
Aims: To determine whether antiosteoporosis treatment promotes tendon-to-bone healing after rotator cuff repair (RCR) in animal models. Methods: This systematic review adhered to the PRISMA guidelines and was registered on PROSPERO (registration number ...
Daijun Xie   +6 more
doaj   +1 more source

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