Results 51 to 60 of about 2,218,829 (249)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Reducing the risk of food borne pathogens (Campylobacter) in pre-slaughter pigs via short-time feeding with prebiotics [PDF]

, 2008
Reducing the presence of human pathogens like Campylobacter and Salmonella (zoonoses) in their animal hosts is important to enhance food safety of products of animal origin.
Baggesen, D.L., Hansen, L.L., Jensen, A.N.   +2 more
core  

Development and Daily Management of an Explicit Strategy of Nonuse of Antimicrobial Drugs in Twelve Danish Organic Dairy Herds [PDF]

, 2006
Promotion of animal health and well-being at the individual animal and herd level is an important goal in organic farming. At the same time, chemical products affecting the natural balance among living organisms are prohibited in all areas of the organic
Bennedsgaard, T.W., Klaas, I.C., Nissen, T.B., Thamsborg, S.M., Vaarst, M., Østergaard, S.   +5 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evaluation of the effectiveness of a thermal hygienization reactor

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011
For reasons of limiting the spread of serious transmissible diseases, with regard to the requirement for reducing landfill of biodegradable waste (which may or contains animal by-products and thus presents a potential risk to human and animal health) and
Daniel Borski
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Responses of intestinal morphology, immunity, antioxidant status and cecal microbiota to the mixture of glycerol monolaurate and cinnamaldehyde in laying hens

Poultry Science
: This study was to determine the effects of the mixture of glycerol monolaurate and cinnamaldehyde (GCM) supplementation on the intestinal morphology, immunity, antioxidant status and cecal microbiota of laying hens. A total of 1,120 healthy laying hens
M.Y. Chen, Y.L. Duan, Y. Zhu, J.H. Wang, Q.B. Hu, S.S. Guo, B.Y. Ding, Z.F. Zhang, L.L. Li   +8 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Methane Production From Animal by-Products and Wastes [PDF]

Journal of Environmental Studies, 2010
This study was carried out in the laboratory of nutrition, College of veterinary medicine and animal production. The study was continued for 30 days. The results obtained in this study were very satisfactory. The mixed treatment (50% poultry droppings + 50% hides) recorded the highest amount of methane (1308cm 3 ), followed by hide by3 products (570cm ...
Daoud Ahmed, Intisar Turki
openaire   +1 more source