Results 71 to 80 of about 2,235,257 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dietary supplementation with farnesol confers a protective effect on the intestine of broiler chickens challenged with lipopolysaccharide by reshaping intestinal flora structure and regulating TLR4/NF-κB signaling pathway

Poultry Science
Farnesol (FAN), one of plant essential oils, is widely found in a variety of natural plants. Studies demonstrated that FAN contributed to the antioxidant and immune function as well as improving the intestinal flora, however effects of it on the broiler ...
Peng Li, Chenyu Guo, Wenfei Tong, Shaochen Han, Xiangxue Sun, Lei Xiao, Qunbing Hu, Yongqing Hou, Binying Ding, Dan Yi   +9 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Dietary supplementary with ellagic acid improves the intestinal barrier function and flora structure of broiler chicken challenged with E. coli K88

Poultry Science
Ellagic acid (EA) contributes to the immunity and anti-oxidant function of body, whereas there are few reports about its effect on the intestinal health and growth performance of broiler chickens.
Peng Li, Shengnan Zhao, Yi Teng, Shaochen Han, Yuzhu Yang, Mengjun Wu, Shuangshuang Guo, Bingying Ding, Lei Xiao, Dan Yi   +9 more
doaj   +1 more source

Statement on technical assistance on the format for applications for new alternative methods for animal by‐products

EFSA Journal, 2010
EFSA's Scientific Panel on Biological Hazards (BIOHAZ) was asked for technical assistance in the development of a standard format for applications for new alternative methods of use and disposal for Animal By‐Products (ABPs).
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Zinc oxide nanoparticles cause hepatotoxicity in rare minnow (Gobiocypris rarus) via ROS-mediated oxidative stress and apoptosis activation and inhibition of lipid peroxidation

Aquaculture Reports
Zinc oxide nanoparticles (ZnO NPs) measuring 30 ± 10 nm in diameter are utilized in various applications, including batteries, plastics, ceramics, cosmetics, flame retardants, and food.
Liangxia Su, Huanhuan Li, Jiahuan Wang, Jinming Wu, Jing Wan, Yongfeng He, Jun Liu   +6 more
doaj   +1 more source

Selection of new markers for animal by-products characterization by classical microscopy

Italian Journal of Animal Science, 2010
The aim of this study was to identify possible markers to distinguish differences between land animals by using the microscopic method in association with computer image analysis. For this purpose bone fragments from poultry and mammals were obtained and
G. Savoini, V. Dell'Orto, C. Paltanin, L. Maggioni, A. Campagnoli, L. Pinotti   +5 more
doaj   +1 more source

Introduction: leather in archaeology, between material properties, materiality and technological choices [PDF]

, 2014
The study of leather is a specialist field in archaeology, yet focuses on one of the major materials in the past, the use of which continues into the present.
Harris, Susanna
core   +1 more source

Reproductive and developmental effects of phthalate diesters in females. [PDF]

, 2013
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina, Foster, Warren G, Kay, Vanessa R   +2 more
core   +1 more source