Results 81 to 90 of about 2,235,257 (308)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Livestock to 2020: the next food revolution [PDF]

A team of researchers from the International Food Policy Research Institute (IFPRI), the Food and Agricultural Organization of the United Nations (FAO), and the International Livestock Research Institute (ILRI) collaborated to produce this comprehensive ...
Courbois, Claude, Delgado, Christopher L., Ehui, Simeon K., Rosegrant, Mark W., Steinfeld, Henning   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Characterization of some Winery by-Products Used in Animal Feeds

Scientific Papers Animal Science and Biotechnologies, 2023
Secondary products from winemaking are considered to be a rich source of bioactive compounds, mainly phenolic compounds, which can offer numerous opportunities to improve feed quality. This paper aims to characterize three winery by-products (grape marc,
Raluca Paula Turcu, Margareta Olteanu, Mariana Ropota, Monica Mitoi, Dumitru Drăgotoiu   +4 more
doaj  

Creation of a public LCA database of French agricultural raw products : agriBALYSE [PDF]

, 2010
ADEME, the French Environment and Energy Management Agency, sees Life Cycle Assessment (LCA) as an essential tool to guide the evolution of agricultural production chains towards environmental sustainability.
Basset-Mens, Claudine, Biard, Yannick, Deltour, L., Gac, Armelle, Gaillard, Gérard, Koch, Peter, Lellahi, Afsaneh, Van Der Werf, Hayo M.G.   +7 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Phloretin supplementation ameliorates intestinal injury of broilers with necrotic enteritis by alleviating inflammation, enhancing antioxidant capacity, regulating intestinal microbiota, and producing plant secondary metabolites

Poultry Science
The present study aimed to explore the effects of dietary phloretin (PT) on growth performance, immune response, and intestinal function in broilers with necrotic enteritis (NE). A total of 288 1-day-old Arbor Acres chicks were assigned to 3 groups, with
Mengjun Wu, Meng Peng, Jiajia Zang, Shaochen Han, Peng Li, Shuangshuang Guo, Giuseppe Maiorano, Qunbing Hu, Yongqing Hou, Dan Yi   +9 more
doaj   +1 more source

Scientific Opinion on Lime Treatment of Solid Pig and Poultry Manure

EFSA Journal, 2010
EFSA's Scientific Panel on Biological Hazards (BIOHAZ) was asked for a scientific opinion on a novel process submitted by a European association as a safe means of disposal of Animal By‐Products (ABP) according to Regulation (EC) 1774/2002 .
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

OrgTrace – No Difference in Levels of Bioactive Compounds found in Crops from Selected Organic and Conventional Cultivation Systems [PDF]

, 2011
The objective of the present study was to compare the content of selected bioactive compounds in organically and conventionally grown crops, and to evaluate if the ability of the crops to synthesize selected secondary metabolites was systematically ...
Bysted, Anette, Halekoh, Ulrich, Husted, Søren, Knuthsen, Pia, Laursen, Kristian Holst, Madsen, Katja H, Nielsen , John, Soeltoft, Malene   +7 more
core