Results 211 to 220 of about 1,350,044 (307)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Study protocol on antimicrobial resistance burden, transmission dynamics, and therapeutic bacteriophages in livestock and exposed farming populations in Nagpur, India: An integrated One Health approach. [PDF]

PLoS One
Nayak AR, Shukla J, Kulkarni S, Biswas R, Kurkure N, Kaore M, Chaudhari S, Bajpai U, Kannan K, Sivanesan S, Sontakke SD, Husain A, Kulurkar PM, Bafna A, Kashyap RS.   +14 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Capnocytophaga canimorsus Bacteremia Without Animal Bite: A Rare but Severe Infection to Consider in Older Adults. [PDF]

Am J Case Rep
Hadid M, Soret J, Sugier M, Azzoug C, Lahaye C.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Isolating and Validating Fibroblast-like Cells from the Skeletal Muscle of the Siamese Crocodile (<i>Crocodylus siamensis</i>). [PDF]

Vet Sci
Akrimajirachoote N, Pattarapanawan M, Chaipipat S, Piyasanti Y, Sritabtim K, Jurutha J, Siripattarapravat K, Setthawong P.   +7 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Cell Culture Versus Animal Experiments

, 1981
Hensten-Pettersen, Arne
core   +1 more source

Comparison of PCR and culture for detection of <i>Campylobacter jejuni</i> in canine feces. [PDF]

J Vet Diagn Invest
Lawhon SD, Cummings KJ, Wu J, Yang CY, Whipple N, Prarat Koscielny M, Lindemann S, Kiener S, Kmet M, Reddy R, Goodman LB, Franklin-Guild RJ, Sams K, Cronk B, Cui J, Lawrence K, Zhang Q, Zhang Y, Ensley S, Olsen K, Tomaszewski J, Shen Z, Zhang S, Dasgupta S, Mann S, Patil A, Thakur S, Rankin SC, Ruesch L, Garcia-Fernandez N, Guag J, Nemser SM, Reimschuessel R.   +32 more
europepmc   +1 more source