Results 81 to 90 of about 7,212,743 (347)

The Influence of Culture on Attitudes Towards Humanoid and Animal‐like Robots: An Integrative Review

Journal of Nursing Scholarship, 2018
PURPOSE The aim of the present review is to explore the influence of culture on attitudes towards humanoid and animal-like robots. DESIGN An integrative review of current evidence.
I. Papadopoulos, C. Koulouglioti
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

The European Federation of the Pharmaceutical Industry and Associations’ Research and Animal Welfare Group: Assessing and benchmarking ‘Culture of Care’ in the context of using animals for scientific purpose

Laboratory Animals. Journal of the Laboratory Animal Science Association, 2019
The European Federation of Pharmaceutical Industries and Associations’ Research and Animal Welfare group members reflected on the concept of a Culture of Care in relation to animal care and use and on differences in its understanding and application ...
Sally Robinson, Sue Sparrow, Bella Williams, T. Decelle, T. Bertelsen, Kirsty Reid, M. Chlebus   +6 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Effects of dietary carbohydrate composition on rumen fermentation characteristics and microbial population in vitro

Italian Journal of Animal Science, 2015
The objective of the experiment was to evaluate the effects of dietary carbohydrate composition on rumen fermentation characteristics and microbial populations in vitro. The treatments were organized in three different carbohydrate composition diets: the
Xiangfei Zhang, Haibo Zhang, Zhisheng Wang, Xiaoming Zhang, Huawei Zhou, Cui Tan, Quanhui Peng   +6 more
doaj   +1 more source

Science, Culture, and Care in Laboratory Animal Research

, 2018
The principles of the 3Rs—replacement, refinement, and reduction—strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience.
G. Davies, B. Greenhough, P. Hobson-West, R. G. Kirk   +3 more
semanticscholar   +1 more source

A Simple Method to Reduce both Lactic Acid and Ammonium Production in Industrial Animal Cell Culture

International Journal of Molecular Sciences, 2018
Fed-batch animal cell culture is the most common method for commercial production of recombinant proteins. However, higher cell densities in these platforms are still limited due to factors such as excessive ammonium production, lactic acid production ...
Nathaniel W. Freund, M. Croughan
semanticscholar   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Effects of High-Grain Diet on Performance, Ruminal Fermentation, and Rumen Microbial Flora of Lactating Holstein Dairy Cows

Animals
The objectives of the current study were to evaluate the fluctuations in production performance, rumen fermentation, and microbial community in lactating dairy cows fed a high-grain diet (HG).
Kexin Wang, Damin Song, Xuelei Zhang, Osmond Datsomor, Maocheng Jiang, Guoqi Zhao   +5 more
doaj   +1 more source

Nutritional Interventions Improved Rumen Functions and Promoted Compensatory Growth of Growth-Retarded Yaks as Revealed by Integrated Transcripts and Microbiome Analyses

Frontiers in Microbiology, 2019
Growth retardation reduces the incomes of livestock farming. However, effective nutritional interventions to promote compensatory growth and the mechanisms involving digestive tract microbiomes and transcripts have yet to be elucidated.
Rui Hu, Huawei Zou, Zhisheng Wang, Binghai Cao, Quanhui Peng, Xiaoping Jing, Yixin Wang, Yaqun Shao, Zhaoxi Pei, Xiangfei Zhang, Bai Xue, Lizhi Wang, Suonan Zhao, Yuqing Zhou, Xiangying Kong   +14 more
doaj   +1 more source