Results 151 to 160 of about 1,485,253 (263)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Assessment of animal diseases caused by bacteria resistant to antimicrobials: Swine. [PDF]

EFSA J, 2021
EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortazar Schmidt C, Herskin M, Michel V, Miranda Chueca MA, Padalino B, Pasquali P, Roberts HC, Sihvonen LH, Spoolder H, Stahl K, Velarde A, Viltrop A, Winckler C, Dewulf J, Guardabassi L, Hilbert F, Mader R, Baldinelli F, Alvarez J.   +26 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Editorial: Proceedings of the Inaugural ISESSAH Conference

Frontiers in Veterinary Science, 2019
Bouda Vosough Ahmadi, Jonathan Rushton, Barbara Häsler, Henk Hogeveen, George John Gunn   +4 more
doaj   +1 more source

Analysis of Cross-Border Movement of Cattle in Yunnan Province, China: Insights Into Transboundary Animal Diseases Control. [PDF]

Transbound Emerg Dis
Meixia D, Ying Y, Hao T, Hanze L, Honglin Y, Chao L, Chaojian S, Yi Z.   +7 more
europepmc   +1 more source

Assessment of animal diseases caused by bacteria resistant to antimicrobials: cattle. [PDF]

EFSA J, 2021
EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortazar Schmidt C, Herskin M, Michel V, Miranda Chueca MA, Padalino B, Pasquali P, Roberts HC, Spoolder H, Stahl K, Velarde A, Viltrop A, Winckler C, Dewulf J, Guardabassi L, Hilbert F, Mader R, Baldinelli F, Alvarez J.   +25 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Editorial: Predicting, managing, and minimizing mycotoxicosis in farm animals

Frontiers in Fungal Biology
Jesús Adonai Maguey-González, Juan D. Latorre, Sergio Gomez-Rosales, Abraham Mendez-Albores   +3 more
doaj   +1 more source

Network Analysis of Small Ruminant Movements in Uganda: Implications for Control of Transboundary Animal Diseases. [PDF]

Transbound Emerg Dis
Nkamwesiga J, Rascón-García K, Lumu P, Kiara H, Perez A, Muhanguzi D, Roesel K.   +6 more
europepmc   +1 more source

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infectious pancreatic necrosis (IPN). [PDF]

EFSA J, 2023
EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Alvarez J, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Rojas JLG, Gortázar C, Herskin MS, Michel V, Miranda MÁ, Padalino B, Pasquali P, Roberts HC, Spoolder H, Ståhl K, Velarde A, Viltrop A, Winckler C, Bron J, Olesen NJ, Sindre H, Stone D, Vendramin N, Antoniou SE, Kohnle L, Papanikolaou A, Karagianni AE, Bicout DJ.   +29 more
europepmc   +1 more source