Results 91 to 100 of about 3,029,727 (288)
Animal Experimentation Ethics Committee B
, 2016 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Special Welfare and Ethical Requirements for Infectious Animal Experiments
Shiyan dongwu yu bijiao yixueInfectious disease animal models serve as indispensable tools for understanding the transmission patterns, pathogenesis, and anti-infective medicine. During the preparation and application of infectious animal disease models, situations inevitably arise ...
MIN Fangui +6 more
doaj +1 more source
Animal research ethics as interaction of research ethics, animal ethics, and (animal protection) law
ALTEX, 2023 Felicitas, Selter +3 more
openaire +2 more sources
From Mice to Monkeys? Beyond orthodox approaches tot he Ethics of Animal Model Choice [PDF]
, 2020 Recent developments in genome editing tools, along with limits in the translational potential of rodent models of human disease, have spurred renewed biomedical research interest in large mammals like nonhuman primates, pigs, and dogs.
Walker, Rebecca L +3 more
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
EVALUATION OF LEFT ATRIUM AND AORTA IN TWO-DIMENSIONAL AND M-MODE ECHOCARDIOGRAPHY IN FEMALE MALABARI GOATS [PDF]
Journal of Veterinary and Animal Sciences, 2018 Left atrial to aortic ratio was evaluated using two-dimensional and M-mode echocardiography in twelve healthy adult female Malabari goats. The normal values of left atrium to aortic ratio in healthyMalabari goats in both the techniques varied ...
K.G. Tejaswini +4 more
doaj
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source