Results 151 to 160 of about 10,859,199 (331)

Post-weaning performance and carcass characteristics of steer progency from different suckler cow breed types [PDF]

, 2005
peer-reviewedIn two experiments a total of 44 steer progeny of spring-calving Charolais (C) and Hereford × Friesian (HF) suckler cows and C sires were slaughtered at approximately 2 years of age.
Drennan, Michael J, Keane, Michael G., McGee, Mark   +2 more
core  

Bone repair with raloxifene and bioglass nanoceramic composite in animal experiment

Connective Tissue Research, 2018
P. Lisboa-Filho, P. H. Gomes-Ferreira, F. R. S. Batista, G. Momesso, L. Faverani, R. Okamoto   +5 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Demethylzeylasteral reduces the level of proteinuria in diabetic nephropathy: Screening of network pharmacology and verification by animal experiment. [PDF]

Pharmacol Res Perspect, 2022
Xu L, Zhao B, Yang L, Dong X, Yang X, Mao Y.   +5 more
europepmc   +1 more source

Policing animal experiments [PDF]

Nature, 1989
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain. [PDF]

Mediators Inflamm, 2022
Xi P, Mao R, Wu S, Liu L, Cai C, Lu L, Zhang C, Li Y.   +7 more
europepmc   +1 more source

CONSUMER VALUATION OF BEEF RIBEYE STEAK ATTRIBUTES [PDF]

A choice experiment (conjoint analysis) was used to investigate consumer demand for several beef ribeye steak attributes. Respondents indicated that they would prefer a "hormone free" ribeye steak priced up to $6.68/lb.
Fox, John A., Lusk, Jayson L.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Biological effects of cinnamaldehyde in animal cancer models: a systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundCinnamaldehyde (CA), a naturally occurring aromatic aldehyde from cinnamon bark, has been investigated for its biological activity in laboratory settings. However, its α,β-unsaturated aldehyde structure designates it as a pan-assay interference
Dan Luo, Xu Luo, Jinghui Xie, Keying Ye, Xiangjin Wang, Xiyue Hu, Chenhao Liu, Yi Liu   +7 more
doaj   +1 more source