Results 111 to 120 of about 26,422,673 (403)
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Estimating genetic parameters in natural populations using the "animal model".
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2004 Estimating the genetic basis of quantitative traits can be tricky for wild populations in natural environments, as environmental variation frequently obscures the underlying evolutionary patterns.
L. Kruuk
semanticscholar +1 more source
Central and peripheral insulin resistance in a large animal model of obesity [PDF]
, 2012 Non peer reviewedPublisher ...
Adam, Clare Lesley +4 more
core +1 more source
Animal Models of Hemophilia [PDF]
, 2012 The X-linked bleeding disorder hemophilia is caused by mutations in coagulation factor VIII (hemophilia A) or factor IX (hemophilia B). Unless prophylactic treatment is provided, patients with severe disease (less than 1% clotting activity) typically experience frequent spontaneous bleeds.
Denise E. Sabatino +5 more
openaire +4 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Gut microbiota affects obesity susceptibility in mice through gut metabolites
Frontiers in MicrobiologyIntroductionIt is well-known that different populations and animals, even experimental animals with the same rearing conditions, differ in their susceptibility to obesity.
Yuhang Wen +37 more
doaj +1 more source
Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit
EMBO Molecular Medicine, 2016 Upon adaption of skeletal muscle to physiological and pathophysiological stimuli, muscle fiber type and mitochondrial function are coordinately regulated.
Jing Liu +13 more
doaj +1 more source
Molecules, 2019 Soy isoflavones (SIF) are biologically active compounds of non-steroidal and phenolic properties that are richly present in soybeans, which can reduce the body weight and blood lipids of obese animals.
Qihui Luo +7 more
doaj +1 more source
Cell Research, 2012 Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal ...
Yiwu Yan +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source