Results 131 to 140 of about 2,034,258 (266)

Syrian hamster is a valuable animal model for evaluating the transmissibility of emerging influenza viruses. [PDF]

Emerg Microbes Infect
Li J, Wang D, Li B, Ma J, He X, Chen L, Kong H, Deng G, Cui P, Yang H, Meng F, Zeng X, Tian G, Shi J, Chen H.   +14 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Characterization of inflammatory pseudotumors in a large animal model of liver cancer. [PDF]

Animal Model Exp Med
Cressman ENK, Hicks S, Fowlkes NW, Stolley DL, Stenkamp MS.   +4 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Protection of metabolic-hemodynamic coupling by nimodipine in an animal model of cerebral small vessel disease. [PDF]

J Cereb Blood Flow Metab
Yang Z, Lange F, Xia Y, Tachtsidis I, Smith KJ.   +4 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Author Correction: The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice

Nature Communications
Jing Wu, Dandan Bu, Haiquan Wang, Di Shen, Danyang Chong, Tongyu Zhang, Weiwei Tao, Mengfei Zhao, Yue Zhao, Lei Fang, Peng Li, Bin Xue, Chao-Jun Li   +12 more
doaj   +1 more source

Efficacy of mebendazole in the spontaneous NZBxNZWF1 animal model of systemic lupus erythematosus. [PDF]

Sci Rep
Eloranta ML, Nygren P, Larsson R, Loskog A, Woodworth N, Hultqvist M, Svensson R, Gravenfors Y, Rönnblom L, Fryknäs M.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Behavioural susceptibility to environmental influences in obesity- evidence from a companion animal model. [PDF]

BMC Vet Res
Morros-Nuevo A, Salt C, Pavey J, F Wainwright J, Dittmann M, Keep B, Wallis NJ, Raffan E.   +7 more
europepmc   +1 more source