Results 121 to 130 of about 2,221,657 (315)
Restricted Maximum Likelihood Estimation of Variance Components for Univariate Animal Models Using Sparse Matrix Techniques and Average Information [PDF]
An algorithm is described to estimate variance components for a univariate animal model using REML. Sparse matrix techniques are employed to calculate those elements of the inverse of the coefficient matrix required for the first derivatives of the ...
JOHNSON, DL, THOMPSON, R
core
Overexpression of mitotic arrest deficiency 2 (MAD2/MAD2L1), a pivotal component of the spindle assembly checkpoint (SAC), resulted in many types of cancer.
Yao Xi +14 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Animal Welfare and Eggs – Cheap Talk or Money on the Counter? [PDF]
We estimate revealed willingness to pay for animal welfare using a panel mixed logit model. We utilize a unique household level panel, combining real purchases with survey data on perceived public and private good attributes of different types of eggs ...
Laura Mørch Andersen
core
MRI of Syrian hamsters reveals SARS-CoV-2 variant-specific neuroinflammation
SARS-CoV-2 infection causes neurological manifestations in 30%–40% of patients, with reinfection exacerbating sequelae risks. Elucidating neuroinvasion mechanisms requires optimized animal models overcoming limitations of existing systems.
Yisi Tang +5 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Valoració per part de l’operador econòmic del model de PNT de benestar animal per a petits escorxadors d’ungulats i solípedes domèstics [PDF]
Benestar animal; Escorxadors; Control oficialBienestar animal; Mataderos; Control oficialAnimal welfare; Slaughterhouses; Official controlA l’anterior treball de la CoP de benestar animal (Model de PNT de benestar animal per a petits escorxadors d ...
Esquius-Calves, Marc +8 more
core
GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas
Temozolomide (TMZ), a DNA alkylating agent, has become the primary treatment for glioma, the most common malignancy of the central nervous system. Although TMZ-containing regimens produce significant clinical response rates, some patients inevitably ...
Hua He +8 more
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source

