Results 131 to 140 of about 27,577,089 (399)

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]

, 2019
Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S, Giza, Christopher C, Hoffman, Ann N, Hovda, David A, Lam, Jamie   +4 more
core   +1 more source

Fission-fusion dynamics and group-size dependent composition in heterogeneous populations

, 2019
Many animal groups are heterogeneous and may even consist of individuals of different species, called mixed-species flocks. Mathematical and computational models of collective animal movement behaviour, however, typically assume that groups and ...
Guttal, Vishwesha, Iyer, Srikanth K., Nair, Gokul G., Senthilnathan, Athmanathan   +3 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model

Cell Research, 2012
Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal ...
Yiwu Yan, Zhen Zou, Yang Sun, Xiao Li, K. Xu, Yuquan Wei, N. Jin, Chengyu Jiang   +7 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Effect of three animal models of inflammation on nerve fibres in the synovium. [PDF]

, 1994
P.I. Mapp, David A. Walsh, Neil Garrett, Bruce Kidd, Simon Cruwys, J. M. Polak, David R. Blake   +6 more
openalex   +1 more source

EVALUATION OF ANTIDEPRESSANT EFFECT OF 6-SHOGAOL IN ANIMAL MODELS

, 2022
PAYAL RAHANGDALE, DEEPAK KUMAR BASEDIYA, Vivek Thakur, BALKRISHNA DUBEY   +3 more
openalex   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

PGC-1α-Coordinated Hypothalamic Antioxidant Defense Is Linked to SP1-LanCL1 Axis during High-Fat-Diet-Induced Obesity in Male Mice

Antioxidants
High-fat-diet (HFD)-induced obesity parallels hypothalamic inflammation and oxidative stress, but the correlations between them are not well-defined. Here, with mouse models targeting the antioxidant gene LanCL1 in the hypothalamus, we demonstrate that ...
Shuai Shi, Jichen Wang, Huan Gong, Xiaohua Huang, Bin Mu, Xiangyu Cheng, Bin Feng, Lanlan Jia, Qihui Luo, Wentao Liu, Zhengli Chen, Chao Huang   +11 more
doaj   +1 more source

Genetic analysis of survival and fitness in turkeys with multiple-trait animal models [PDF]

, 2011
Cheryl Quinton, Benjamin J. Wood, Stephen P. Miller   +2 more
openalex   +1 more source