Results 11 to 20 of about 27,577,089 (399)

Zebrafish as an animal model for biomedical research

open access: yesExperimental and Molecular Medicine, 2021
Zebrafish have several advantages compared to other vertebrate models used in modeling human diseases, particularly for large-scale genetic mutant and therapeutic compound screenings, and other biomedical research applications.
Tae-Young Choi   +4 more
semanticscholar   +1 more source

Folic acid‐induced animal model of kidney disease

open access: yesAnimal Models and Experimental Medicine, 2021
The kidneys are a vital organ that is vulnerable to both acute kidney injury (AKI) and chronic kidney disease (CKD) which can be caused by numerous risk factors such as ischemia, sepsis, drug toxicity and drug overdose, exposure to heavy metals, and ...
Liang-Jun Yan
semanticscholar   +1 more source

The Problem of Wound Healing in Diabetes—From Molecular Pathways to the Design of an Animal Model

open access: yesInternational Journal of Molecular Sciences, 2022
Chronic wounds are becoming an increasingly common clinical problem due to an aging population and an increased incidence of diabetes, atherosclerosis, and venous insufficiency, which are the conditions that impair and delay the healing process. Patients
M. Mieczkowski   +4 more
semanticscholar   +1 more source

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

open access: yesScience, 2020
Protective neutralizing antibodies Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute ...
T. Rogers   +33 more
semanticscholar   +1 more source

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Since SARS-CoV-2 emerged in China, it has spread rapidly around the world. Effective vaccines and therapeutics for SARS-CoV-2−induced disease (coronavirus disease 2019;COVID-19) are urgently needed.
M. Imai   +33 more
semanticscholar   +1 more source

An Animal Model of Inhaled Vitamin E Acetate and EVALI-like Lung Injury.

open access: yesNew England Journal of Medicine, 2020
An Animal Model of EVALI In this study, investigators developed a mouse model of e-cigarette, or vaping, product use–associated lung injury.
T. A. Bhat   +5 more
semanticscholar   +1 more source

Novel Circulating Tumour Cell-Related Risk Model Indicates Prognosis and Immune Infiltration in Lung Adenocarcinoma

open access: yesJournal of Immunology Research, 2022
Background. Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer (LC) and one of the leading causes of cancer-related death worldwide. LUAD has a low survival rate owing to tumour invasion and metastasis.
Lu Liang   +7 more
doaj   +1 more source

Methoxychlor induces oxidative stress and impairs early embryonic development in pigs

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Methoxychlor (MXC) is an organochlorine pesticide (OCP) that was formerly used worldwide as an insecticide against pests and mosquitoes. However, MXC is not biodegradable and has lipophilic characteristics; thus, it accumulates in organisms
Zhaojun Geng   +10 more
doaj   +1 more source

Zebrafish as an alternative animal model in human and animal vaccination research

open access: yesLaboratory Animal Research, 2020
Much of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of innovative therapies.
R. Bailone   +8 more
semanticscholar   +1 more source

Zebrafish as animal model for aquaculture nutrition research. [PDF]

open access: yes, 2014
The aquaculture industry continues to promote the diversification of ingredients used in aquafeed in order to achieve a more sustainable aquaculture production system. The evaluation of large numbers of diets in aquaculture species is costly and requires
Feijoo, Carmen G   +2 more
core   +2 more sources

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