Results 11 to 20 of about 3,851,825 (350)
Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction
Frontiers in Physiology, 2020 Both smooth muscle (SM) and non-muscle (NM) myosin II are expressed in hollow organs such as the bladder and uterus, but their respective roles in contraction and corresponding physiological functions remain to be determined.
Jie Sun +13 more
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Journal of Immunology Research, 2022 Background. Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer (LC) and one of the leading causes of cancer-related death worldwide. LUAD has a low survival rate owing to tumour invasion and metastasis.
Lu Liang +7 more
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Animal models of preeclampsia [PDF]
Seminars in Nephrology, 1999 There have been many attempts to produce animal models that mimic the hypertensive disorders of pregnancy, especially preeclampsia, but most are incomplete when compared to the full spectrum of the human disease. This review assesses a number of these models, organized according to the investigators attempt to focus on a specific pathogenic mechanism ...
Chris Baylis +8 more
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Methoxychlor induces oxidative stress and impairs early embryonic development in pigs
Frontiers in Cell and Developmental Biology, 2023 Introduction: Methoxychlor (MXC) is an organochlorine pesticide (OCP) that was formerly used worldwide as an insecticide against pests and mosquitoes. However, MXC is not biodegradable and has lipophilic characteristics; thus, it accumulates in organisms
Zhaojun Geng +10 more
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PER1 Phosphorylation Specifies Feeding Rhythm in Mice
Cell Reports, 2014 Organization of circadian behavior, physiology, and metabolism is important for human health. An S662G mutation in hPER2 has been linked to familial advanced sleep-phase syndrome (FASPS).
Zhiwei Liu +10 more
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Scientific Reports, 2022 The use of minipigs (Sus scrofa) as a platform for toxicological and pharmacological research is well established. In the present study, we investigated the effect of formaldehyde (FA) exposure on helper T cell-mediated splenic immune responses in ...
Jeongsik Park +5 more
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Zebrafish as animal model for aquaculture nutrition research. [PDF]
, 2014 The aquaculture industry continues to promote the diversification of ingredients used in aquafeed in order to achieve a more sustainable aquaculture production system. The evaluation of large numbers of diets in aquaculture species is costly and requires
Feijoo, Carmen G +2 more
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Animal Models in Osteosarcoma [PDF]
Frontiers in Oncology, 2014 Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to rapidly develop pulmonary metastases.
C. Parker Gibbs +2 more
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ACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans
Nature Communications, 2023 Dietary restriction is an effective anti-ageing intervention across species. However, the molecular mechanisms from the metabolic aspects of view are still underexplored. Here we show ACS-20 as a key mediator of dietary restriction on healthy ageing from
Zi Wang +12 more
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Fundamental Moral Attitudes to Animals and Their Role in Judgment: An Empirical Model to Describe Fundamental Moral Attitudes to Animals and Their Role in Judgment on the Culling of Healthy Animals During an Animal Disease Epidemic [PDF]
, 2009 In this paper, we present and defend the theoretical framework of an empirical model to describe people’s fundamental moral attitudes (FMAs) to animals, the stratification of FMAs in society and the role of FMAs in judgment on the culling of healthy ...
Brom, F.W.A., Cohen, N.E., Stassen, E.N.
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