Results 31 to 40 of about 26,422,673 (403)
BMC Cancer, 2023 Background Oral squamous cell carcinoma (OSCC) is a common malignant tumor associated with poor prognosis. MicroRNAs (miRNAs) play crucial regulatory roles in the cancer development.
Guoqiang Xu +11 more
doaj +1 more source
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
Journal of Neuroinflammation, 2019 Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and generates ...
Dezhen Tu +5 more
doaj +1 more source
Selecting an Appropriate Animal Model of Depression
International Journal of Molecular Sciences, 2019 Depression has become one of the most severe psychiatric disorders and endangers the health of living beings all over the world. In order to explore the molecular mechanism that underlies depression, different kinds of animal models of depression are ...
Yuanzhen Hao +3 more
semanticscholar +1 more source
Role of animal models in biomedical research: a review
Laboratory Animal Research, 2022 The animal model deals with the species other than the human, as it can imitate the disease progression, its’ diagnosis as well as a treatment similar to human.
P. Mukherjee, S. Roy, D. Ghosh, S. Nandi
semanticscholar +1 more source
Maxillary expansion in an animal model with light, continuous force [PDF]
, 2018 Objectives: Maxillary constriction is routinely addressed with rapid maxillary expansion (RME). However, the heavy forces delivered by most RME appliances to expand the palate may lead to deleterious effects on the teeth and supporting tissues.
AlRasheed, Rawan +6 more
core +1 more source
Syrian Hamster as an Animal Model for the Study on Infectious Diseases
Frontiers in Immunology, 2019 Infectious diseases still remain one of the biggest challenges for human health. In order to gain a better understanding of the pathogenesis of infectious diseases and develop effective diagnostic tools, therapeutic agents, and preventive vaccines, a ...
Jinxin Miao +3 more
semanticscholar +1 more source
Probabilistic models of individual and collective animal behavior [PDF]
, 2017 Recent developments in automated tracking allow uninterrupted, high-resolution recording of animal trajectories, sometimes coupled with the identification of stereotyped changes of body pose or other behaviors of interest.
Bodova, Katarina +4 more
core +6 more sources
Choosing the right animal model for infectious disease research
Animal Models and Experimental Medicine, 2018 A complex biological system is often required to study the myriad of host‐pathogen interactions associated with infectious diseases, especially since the current basis of biology has reached the molecular level.
J. Swearengen
semanticscholar +1 more source
The 2020 Five Domains Model: Including Human–Animal Interactions in Assessments of Animal Welfare
Animals, 2020 Simple Summary This review outlines the latest in a succession of updates of the Five Domains Model, which, at each stage, incorporated contemporary verified scientific thinking of relevance to animal welfare assessment.
D. Mellor +6 more
semanticscholar +1 more source
Animal Models of Dyssynchrony [PDF]
Journal of Cardiovascular Translational Research, 2011 Cardiac resynchronization therapy (CRT) is an important therapy for patients with heart failure and conduction pathology, but the benefits are heterogeneous between patients and approximately a third of patients do not show signs of clinical or echocardiographic response.
Lars B. van Middendorp +2 more
openaire +2 more sources