Results 11 to 20 of about 2,220,916 (268)

Does the Animal Model Influence in Vertical Alveolar Distraction? A Systematic Review of the Literature. [PDF]

, 2020
This study is aimed at synthesizing all available evidence on vertical alveolar osteogenesis distraction (VAOD) in animal trials to determine whether the animal model used and its handling influence or not, and find which is the most appropriate animal ...
García-González, Mario, González-Cantalapiedra, Antonio, Muñoz, Fernando, López-Peña, Mónica, Mario García-González, Fernando Muñoz, Saulacic, Nikola, González Cantalapiedra, Antonio, Nikola Saulacic, Antonio González-Cantalapiedra, Muñoz Guzón, Fernando María, Mónica López-Peña, García González, Mario, López Peña, Mónica   +13 more
core   +1 more source

Application of the Five Domains model to food chain management of animal welfare: opportunities and constraints

, 2023
For businesses involved in animal production, ensuring high animal welfare standards has become the cornerstone of corporate social responsibility practices.
Croney CC, Swanson JC, McKeegan DEF, Beausoleil NJ   +3 more
core   +1 more source

Formaldehyde exposure induces differentiation of regulatory T cells via the NFAT-mediated T cell receptor signalling pathway in Yucatan minipigs

Scientific Reports, 2022
The use of minipigs (Sus scrofa) as a platform for toxicological and pharmacological research is well established. In the present study, we investigated the effect of formaldehyde (FA) exposure on helper T cell-mediated splenic immune responses in ...
Jeongsik Park, Goo-Hwa Kang, Youngkyu Kim, Ju Young Lee, Jeong Ah Song, Jeong Ho Hwang   +5 more
doaj   +1 more source

Systems biology in animal sciences [PDF]

, 2011
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Pas, M.F.W., te, M.A. Smits, Veerkamp, R.F., Woelders, H., Bannink, A., M.F.W. Te Pas, Pas, M., R.F. Veerkamp, Smits, M.A., H. Woelders, A. Bannink, te Pas, M.F.W.   +11 more
core   +1 more source

Risk factors and genetic parameters of longevity in Spanish dairy goat breeds using a Weibull proportional hazards model [PDF]

, 2023
The aim of this study was to assess the most important risk factors that influence productive life (PL) and to estimate genetic parameters for PL using a Weibull proportional hazards model in two Spanish dairy goat breeds belonging to different ...
Ziadi, Chiraz, Molina, Antonio, Sánchez, Juan Pablo, Sánchez, Manuel   +3 more
core   +1 more source

Spatiotemporal regulation of insulin signaling by liquid–liquid phase separation

Cell Discovery, 2022
Insulin signals through its receptor to recruit insulin receptor substrates (IRS) and phosphatidylinositol 3-kinase (PI3K) to the plasma membrane for production of phosphatidylinositol-3,4,5-trisphosphate (PIP3) from phosphatidylinositol-4,5-bisphosphate
Kun Zhou, Qiaoli Chen, Jiamou Chen, Derong Liang, Weikuan Feng, Minjun Liu, Qi Wang, Ruizhen Wang, Qian Ouyang, Chao Quan, Shuai Chen   +10 more
doaj   +1 more source

The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration

Journal of Neuroinflammation, 2019
Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and generates ...
Dezhen Tu, Yun Gao, Ru Yang, Tian Guan, Jau-Shyong Hong, Hui-Ming Gao   +5 more
doaj   +1 more source

204个国家和地区1990‐2019年因空腹血糖升高导致的全球卒中疾病负担:全球疾病负担研究分析

Journal of Diabetes, 2022
Background High fasting plasma glucose (HFPG) is the leading risk factor contributing to the increase of stroke burden in the past three decades. However, the global distribution of stroke burden specifically attributable to HFPG was not studied in depth.
Yang Liu, Wenxin Wang, Xuewei Huang, Xingyuan Zhang, Lijin Lin, Juan‐Juan Qin, Fang Lei, Jingjing Cai, Bo Cheng   +8 more
doaj   +1 more source

Combinatorial Control of Recruitment of a Variant PRC1.6 Complex in Embryonic Stem Cells

Cell Reports, 2018
Summary: Though genetic data suggest that Polycomb group proteins (PcGs) are central chromatin modifiers and repressors that have been implicated in control of embryonic stem cell (ESC) pluripotency, the precise mechanism of PcG complex recruitment ...
Yikai Huang, Wukui Zhao, Congcong Wang, Yaru Zhu, Mengjie Liu, Huan Tong, Yin Xia, Qing Jiang, Jinzhong Qin   +8 more
doaj   +1 more source

ACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans

Nature Communications, 2023
Dietary restriction is an effective anti-ageing intervention across species. However, the molecular mechanisms from the metabolic aspects of view are still underexplored. Here we show ACS-20 as a key mediator of dietary restriction on healthy ageing from
Zi Wang, Lina Zou, Yiyan Zhang, Mengnan Zhu, Shuxian Zhang, Di Wu, Jianfeng Lan, Xiao Zang, Qi Wang, Hanxin Zhang, Zixing Wu, Huanhu Zhu, Di Chen   +12 more
doaj   +1 more source