Results 91 to 100 of about 2,537,384 (294)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Glutathione mitigates hypoxia-induced gill damage in juvenile grass carp (Ctenopharyngodon idellus) by alleviating endoplasmic reticulum stress and autophagy

Journal of Animal Science and Biotechnology
Background Environmental hypoxia is a common phenomenon in aquaculture, which causes gill tissue injury in fish. Glutathione (GSH) is a vital antioxidant in animal tissues, and its levels decrease under hypoxic conditions.
Shenghua Zeng, Lin Feng, Pei Wu, Yang Liu, Yaobin Ma, Hongmei Ren, Xiaowan Jin, Xiaoqiu Zhou, Weidan Jiang   +8 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Alginate oligosaccharide-induced intestinal morphology, barrier function and epithelium apoptosis modifications have beneficial effects on the growth performance of weaned pigs

Journal of Animal Science and Biotechnology, 2018
Background Alginate oligosaccharide (AOS), produced from alginate by alginate lyase-mediated depolymerisation, is a potential substitute for antibiotics and possesses growth-enhancing effects.
Jin Wan, Jiao Zhang, Daiwen Chen, Bing Yu, Xiangbing Mao, Ping Zheng, Jie Yu, Junqiu Luo, Jun He   +8 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

National Animal Nutrition Program (NANP) Feed Composition Database

, 2018
This database was developed by the Feed Composition Sub-Committee and serves as a freely-available, centralized resource for up-to-date nutrient composition data for feedstuffs commonly fed to animal species.
National Animal Nutrition Program (17479299)
core  

Heat stress induced testicular impairment is related to orchitis and complement activation in Rongchang boars

Journal of Animal Science and Biotechnology
Background Heat stress (HS) is posing as a tremendous threat to the swine industry, due to the thermos-sensitive gonads of boars. Testes are immune-privileged organs in which spermatogenesis needs to remain undisturbed, whereas immune cells are thermo ...
Xiangyuan Ma, Wenxue Shen, Junhao Ni, Xihao Luo, Lianqiang Che, Bin Feng, Lun Hua, Yong Zhuo, Zhengfeng Fang, Shengyu Xu, Jian Li, Xuemei Jiang, Yan Lin, De Wu   +13 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

All-trans retinoic acid alleviates transmissible gastroenteritis virus-induced intestinal inflammation and barrier dysfunction in weaned piglets

Journal of Animal Science and Biotechnology
Background Transmissible gastroenteritis virus (TGEV) is one of the main pathogens causing severe diarrhea of piglets. The pathogenesis of TGEV is closely related to intestinal inflammation. All-trans retinoic acid (ATRA) is the main active metabolite of
Junning Pu, Daiwen Chen, Gang Tian, Jun He, Ping Zheng, Zhiqing Huang, Xiangbing Mao, Jie Yu, Yuheng Luo, Junqiu Luo, Hui Yan, Aimin Wu, Bing Yu   +12 more
doaj   +1 more source