Results 11 to 20 of about 20,896 (257)

Performance Assessment of a Preclinical PET Scanner with Pinhole Collimation by Comparison to a Coincidence-Based Small-Animal PET Scanner [PDF]

Journal of Nuclear Medicine, 2014
PET imaging of rodents is increasingly used in preclinical research, but its utility is limited by spatial resolution and signal-to-noise ratio of the images. A recently developed preclinical PET system uses a clustered-pinhole collimator, enabling high-resolution, simultaneous imaging of PET and SPECT tracers. Pinhole collimation strongly departs from
Matthew D, Walker, Marlies C, Goorden, Katherine, Dinelle, Ruud M, Ramakers, Stephan, Blinder, Maryam, Shirmohammad, Frans, van der Have, Freek J, Beekman, Vesna, Sossi   +8 more
openaire   +2 more sources

Spatial Resolution and Sensitivity of the Inveon Small-Animal PET Scanner [PDF]

Journal of Nuclear Medicine, 2009
The Inveon small-animal PET scanner is characterized by a large, 127-mm axial length and a 161-mm crystal ring diameter. The associated high sensitivity is obtained by using all lines of response (LORs) up to the maximum ring difference (MRD) of 79, for which the most oblique LORs form acceptance angles of 38.3 degrees with transaxial planes.
Visser, E.P., Disselhorst, J.A., Brom, M., Laverman, P., Gotthardt, M., Oyen, W.J.G., Boerman, O.C.   +6 more
openaire   +3 more sources

Validation of PeneloPET against two small animal PET scanners [PDF]

2007 IEEE Nuclear Science Symposium Conference Record, 2007
PeneloPET is a Monte Carlo application based on PENELOPE. We present here the new features and results of validation tests for the new version of PeneloPET that has been compared against data from real scanners. PeneloPET was built as a powerful tool for PET simulation, it is easy to use, fast and very accurate.
España, Samuel, Herraiz, J. L., Vicente, Esther, Herranz, Elena, Vaquero López, Juan José, Desco Menéndez, Manuel, Udías, José Manuel   +6 more
openaire   +2 more sources

Understanding the importance of quality control and quality assurance in preclinical PET/CT imaging

EJNMMI Physics, 2022
The fundamental principle of experimental design is to ensure efficiency and efficacy of the performed experiments. Therefore, it behoves the researcher to gain knowledge of the technological equipment to be used.
Wendy A. McDougald, Julia G. Mannheim
doaj   +1 more source

Influence of Multiple Animal Scanning on Image Quality for the Sedecal SuperArgus2R Preclinical PET Scanner

Frontiers in Physics, 2021
Background: Increased throughput in small animal preclinical studies using positron emission tomography leads to reduced costs and improved efficiency of experimental design, however the presence of multiple off-centre subjects, as opposed to a single ...
Nikos Efthimiou, Nikos Efthimiou, John D. Wright, Luke Clayton, Isaline Renard, Federico Zagni, Paulo R.R.V. Caribé, Stephen J. Archibald, Stephen J. Archibald, Christopher J. Cawthorne, Christopher J. Cawthorne   +10 more
doaj   +1 more source

Comparison of the Amyloid Load in the Brains of Two Transgenic Alzheimer’s Disease Mouse Models Quantified by Florbetaben Positron Emission Tomography

Frontiers in Neuroscience, 2021
Alzheimer’s disease (AD) is characterized by formation of amyloid plaques and neurofibrillary tangles in the brain, which can be mimicked by transgenic mouse models.
Antje Willuweit, Michael Schöneck, Sarah Schemmert, Philipp Lohmann, Philipp Lohmann, Saskia Bremen, Dominik Honold, Nicole Burda, Nan Jiang, Simone Beer, Johannes Ermert, Dieter Willbold, Dieter Willbold, N. Jon Shah, N. Jon Shah, N. Jon Shah, Karl-Josef Langen, Karl-Josef Langen   +17 more
doaj   +1 more source

Characterization of the Ferrara animal PET scanner

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2002
A dedicated small animal PET scanner, YAPPET, was designed and built at Ferrara University. Each detector consists of a 20 20 matrix of 2 2 30 mm 3 YAP:Ce finger-like crystals glued together and directly coupled to a Hamamatsu position sensitive photomultiplier. The scanner is made from four detectors positioned on a rotating gantry at a distance of
DI DOMENICO, Giovanni, MOTTA, Alfonso, ZAVATTINI, Guido, DEL GUERRA, Alberto, DAMIANI, Chiara, BETTINARDI V, GILARDI MC   +6 more
openaire   +2 more sources

Image quality assessment using NEMA NU 4/2008 standards in small animal PET scanner

Brazilian Journal of Radiation Sciences, 2019
In Brazil, there are few microPET in use and a quality control protocols standardization are needed to harmonize their use in the research field. Thus, the purpose of this study is to characterize the image quality performance of the microPET scanner ...
Andréa Vidal Ferreira, Rodrigo Modesto Gadelha Gontijo, Juliana Batista Silva, Marcelo Henrique Mamede   +3 more
doaj   +3 more sources

Cardiac 18F-FDG Positron Emission Tomography: An Accurate Tool to Monitor In vivo Metabolic and Functional Alterations in Murine Myocardial Infarction

Frontiers in Cardiovascular Medicine, 2021
Cardiac monitoring after murine myocardial infarction, using serial non-invasive cardiac 18F-FDG positron emissions tomography (PET) represents a suitable and accurate tool for in vivo studies.
Maximilian Fischer, Maximilian Fischer, Mathias J. Zacherl, Ludwig Weckbach, Ludwig Weckbach, Lisa Paintmayer, Tobias Weinberger, Tobias Weinberger, Konstantin Stark, Konstantin Stark, Steffen Massberg, Steffen Massberg, Peter Bartenstein, Sebastian Lehner, Sebastian Lehner, Christian Schulz, Christian Schulz, Andrei Todica   +17 more
doaj   +1 more source

Influence of image reconstruction protocols on the image quality of a small animal PET scanner using 18F and 11C

Brazilian Journal of Radiation Sciences, 2021
The small animal positron emission tomography (PET) scanner from Molecular Imaging Laboratory (LIM/CDTN) is dedicated to pre-clinical studies on new 18F and 11C-based radiopharmaceuticals and to development of novel applications for well-known ...
João Vitor do Carmo Barbosa, Rodrigo Modesto Gadelha Gontijo, Guilherme Cavalcante de Albuquerque Souza, Bruno Melo Mendes, Juliana Batista da Silva, Marcelo Mamede, Andréa Vidal Ferreira   +6 more
doaj   +1 more source