Results 111 to 120 of about 553,501 (299)
Studies of the control of thyroid function in marsupials / by P.J. Setchell
, 1974 xv, 158 leaves : ill. ; 30 cm.Thesis (Ph.D.)--University of Adelaide, Dept.
Setchell, Peter John
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
iScienceSummary: Obstructive sleep apnea (OSA) induces intermittent hypoxia (IH), an independent risk factor for non-alcoholic fatty liver disease (NAFLD). While the molecular links between IH and NAFLD progression are unclear, immune cell-driven inflammation ...
Jonathan Gaucher +17 more
doaj +1 more source
Control of cholesterol synthesis in precancerous liver
, 1972 xii, 230 p. : ill.Thesis (Ph.D.) -- University of Adelaide, Dept.
Horton, Brian John
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Animal Physiology (5th edition)
, 2021 Comprehensive, contemporary, and engaging, Animal Physiology provides evolutionary and ecological context to help students make connections across all levels of physiological scale. Source: Publisherhttps://scholarworks.smith.edu/bio_books/1001/thumbnail.
Cavanaugh, Daniel +2 more
core
, 2020 Higher milk yield and prolificacy of the modern dairy cattle requires high metabolism activities to support them. It causes high heat production by the body, which coupled with increasing environmental temperatures results in heat stress (HS). Production,
Abdul Sammad +7 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Effects of alterations in potassium intake on body fluids and renal function of merino sheep
, 1969 197 [41] 6 leavesThesis (Ph.D.) -- University of Adelaide, Dept.
Peter, Duncan Wilbur
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source