Results 51 to 60 of about 1,621,199 (300)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The use of animals in laboratories is a controversial issue involving much dispute between the researchers who support animal experimentation and those who are in favor of its abolishment.
Susanna Penco, Rosagemma Ciliberti
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Virna - a database on organic food production [PDF]
Virna is an article reference database on organic food production. It contains material about such matters as organic and ecological crop production and horticulture, soil, fertilization, plant protection, animal production, processing of organic ...
Koistinen, Riitta
core
Sticky bacteriophage protect animal cells [PDF]
For decades, biologists have discussed and experimented with bacterial viruses, called phage, as a means of treating bacterial infections (1, 2). Remarkably, our own evolution may have beaten us to it. In PNAS, Barr et al. present a compelling and unique hypothesis that animal cells use phage as weapons against bacterial pathogens (3).
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Illusory or effective? The protection provided by the Romanian authorities to stray dogs [PDF]
The problem that Romania has with stray dogs’ management is well known at national level, but also intensely debated internationally. The main accusation brought against Romania is the authorities’ noncompliance with the principle of minimum suffering ...
Tatiana-Lăcrămioara Șoldănescu
doaj
BENCHMARKING OF ANTIBODY TITRES SELECTIONS USING THE RANKING METHOD
Based on the serological monitoring results the humoral immunity level in birds was assessed after the use of three variants of inactivated vaccines against avian influenza, which causative agent is capable of genetic rearrangements and generation of ...
V. Yu. Kulakov +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

