Results 121 to 130 of about 759,637 (306)
Are Dairy Cow Replacement Decisions Economically Justified? Evidence from Swiss Farms
AnimalsFarmers frequently face the decision to retain or replace dairy cows, with 20% to 40% of cows replaced annually. In Switzerland, this translates to over 100,000 cows replaced each year, representing a significant financial investment for farms and the ...
Simon Schlebusch +3 more
doaj +1 more source
Unravelling collembolan life belowground: Stoichiometry, metabolism and release of carbon and nitrogen [PDF]
, 2007 This thesis investigated carbon and nitrogen dynamics of soil dwelling Collembola by using direct measurements and stable isotope additions. In an isotope change experiment, collembolans exchanged between 6 and 10% of carbon and nitrogen in their body ...
Larsen, Thomas
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Death Is Unconstitutional: How Capital Punishment Became Illegal in America—A Future History [PDF]
, 2008 [Excerpt] “A constitution is an organic fact of every state: it is a part of the being of the state. People, like the state, also have a constitution—a character. Just as people change over time, so do states. But just as there are natural limits on what
Engle, Jur. Eric, Ph.D.
core +1 more source
Advanced In Vitro Models for Replacement of Animal Experiments [PDF]
Small, 2021 Martin Clift, Shareen Doak
openaire +4 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Explant Analysis of Total Disc Replacement [PDF]
, 2006 Explant analysis of human disc prostheses allow early evaluation of the host response to the prosthesis and the response of the prosthesis from the host. Furthermore, early predictions of failure and wear can be obtained.
Anderson, Paul A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The Role of Sex Hormones in Inducing Maternal Uterine Remodeling and Vasodilation During Pregnancy [PDF]
, 2018 Uterine vascular adaptations such as vessel growth and vasodilation are needed to facilitate the more than 10-fold increase of uteroplacental blood flow (UPBF) during pregnancy.
Glessner-Fischer, Annie D.
core +1 more source