Results 1 to 10 of about 113,516 (292)

The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells [PDF]

Biochemical and Biophysical Research Communications, 2009
Developing effective drug therapies for arrhythmic diseases is hampered by the fact that the same drug can work well in some individuals but not in others.
Shiro Baba, Akira Niwa, Shinya Yamanaka   +2 more
exaly   +2 more sources

Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology

Nature Protocols, 2009
To date, there is no suitable in vitro model to study human adult cardiac cell biology. Although embryonic stem cells are able to differentiate into cardiomyocytes in vitro, the efficiency of this process is very low. Other methods to differentiate progenitor cells into beating cardiomyocytes rely on coculturing with rat neonatal cardiomyocytes, making
Anke M, Smits, Patrick, van Vliet, Corina H, Metz, Tom, Korfage, Joost Pg, Sluijter, Pieter A, Doevendans, Marie-José, Goumans   +6 more
openaire   +2 more sources

Determining TRPM7 in human cardiomyocytes

2018
Introduction. hTRPM7 is a protein that in humans is encoded by the TRPM7 gene, which appears to be ubiquitously expressed with highest expression in heart, and is thought to be involved in magnesium homeostasis as well as in disease processes like atrial fibrillation.
Andriulė, Inga, Almanaitytė, Mantė, Jekabsone, Aistė, Mačianskienė, Regina   +3 more
openaire   +1 more source

Variability of ploidy of human cardiomyocytes

Bulletin of Experimental Biology and Medicine, 1989
V. Ya. Brodskii, I. A. Vasil'eva, N. V. Panova, D. S. Sarkisov, A. M. Aref'eva   +4 more
openaire   +1 more source

[Ploidies of cardiomyocytes in human myocardial hypertrophy].

Biulleten' eksperimental'noi biologii i meditsiny, 1992
DNA cytophotometry has been performed in ventricular cardiomyocytes of hypertrophic human hearts. In the cases of hypertrophy in adults (generalized atherosclerosis, postinfarct scars), polyploidy expression did not exceed the limits of normal variability developed during childhood.
V Ia, Brodskiĭ, A M, Aref'eva, N V, Panova, I G, Gvazava, D S, Sarkisov   +4 more
openaire   +1 more source

In Silico Modeling of Human iPS Cardiomyocytes: Effect of Drugs and Comparison to Human Adult Cardiomyocytes

Journal of Pharmacological and Toxicological Methods, 2017
Michelangelo Paci, Elisa Passini, Stefano Severi, Jari Hyttinen, Blanca Rodriguez   +4 more
openaire   +1 more source

Human iPSC-Derived Cardiomyocytes

Genetic Engineering & Biotechnology News, 2012
openaire   +1 more source

Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro – Correlation between contraction force and electrophysiology

Biomaterials, 2015
Marcelo C Ribeiro, Juan Antonio Guadix, Milena Bellin   +2 more
exaly  

Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells

Journal of Molecular and Cellular Cardiology, 2014
Marita Rodríguez, Lil Pabon, Hans Reinecke   +2 more
exaly  

Silicon Nanowire-Induced Maturation of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

Nano Letters, 2015
Yu Tan, Dylan Richards, Donald R Menick   +2 more
exaly