Results 111 to 120 of about 321,984 (308)
Replacement of Animal Fat by Canola Oil in Chicken Meatball [PDF]
, 2019 This work aimed to develop chicken meatballs with five levels of animal fat replacement by canola oil and to evaluate the product’s behavior during 120 days of storage.
DC Sousa (7856564) +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Reducing the Environmental Impact of Animal Production [PDF]
, 2018 Global food demand will increase in the next 30 years to meet the needs of the increasing population. Demand for animal products (meat, milk and eggs) is likely to increase at a faster rate than the demand for cereals.
Garnsworthy, Phil C.
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Rock phosphate as replacement for bone meal in rabbit diets [PDF]
, 2021 Bone meal as mineral source has become unattractive for animal diets in developed countries due to fear of diseases transfer from animal to animal. Twenty four (24) mongrel weaned rabbits weighing 291.67±3.23 g were randomly allotted to six dietary ...
Kaankuka, F.G. +2 more
core +1 more source
Responses of Rainbow Trout to Fishmeal Replacement with Terrestrial/Aerial Animal Proteins
FishesResearch designed to reduce or eliminate fishmeal (FM) in trout feeds, for reasons that have changed over time, has been conducted for over a century. Reducing the dependency on FM remains one of the most urgent issues facing the industry.
Ewen McLean +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Milk feeding and calf housing practices on British Columbia dairy farms
Journal of Dairy Science: Decades of research have helped inform practices on how to care for calves, but little is known about how well these practices are adopted on commercial dairy farms.
Elizabeth R. Russell +2 more
doaj +1 more source