Results 251 to 260 of about 759,637 (306)

Brazil Moves Toward the Replacement of Animal Experimentation

ATLA Alternatives To Laboratory Animals, 2019
In Brazil, efforts towards the regulatory acceptance and implementation of innovative methods to replace experimental animal use in various fields began to gather force in 2008, with the approval of Law No. 11,794/2008 (the Arouca Law). This law represented a milestone, as it created the National Council for the Control of Animal Experimentation ...
Renato Ivan De Avila   +1 more
exaly   +3 more sources

Management of Replacement Breeding Animals

Veterinary Clinics of North America: Food Animal Practice, 1992
In conclusion, replacement gilts should be finally selected before 110 kg body weight and should have been stimulated to reach puberty by this time. Currently, the best method for achieving this is ad libitum feeding and the correct use of boar exposure.
R N, Kirkwood, P A, Thacker
openaire   +2 more sources

Strategies for replacing animals in biomedical research

Molecular Medicine Today, 1997
In 1959, Russell and Burch published their recommendations for applying the Three Rs (reduction, refinement and replacement alternatives) to the use of animals in scientific experimentation. At this time, they could not have predicted the effect of this fundamental concept on academic and industrial animal experimentation and in biomedical education ...
C L, Broadhead, K, Bottrill
openaire   +2 more sources

The Replacement of Animal Tests

Alternatives to Laboratory Animals, 2018
Progress toward the acceptance and application of validated alternative test methods as replacements for animal tests, is being frustrated by the unsatisfactory procedures involved in approving new test guidelines and deleting existing ones
openaire   +2 more sources

Replacing animal experiments: choices, chances and challenges

BioEssays, 2007
AbstractReplacing animal procedures with methods such as cells and tissues in vitro, volunteer studies, physicochemical techniques and computer modelling, is driven by legislative, scientific and moral imperatives. Non‐animal approaches are now considered as advanced methods that can overcome many of the limitations of animal experiments.
Langley, Gill   +3 more
openaire   +3 more sources

Pulmonary in vitro instruments for the replacement of animal experiments

European Journal of Pharmaceutics and Biopharmaceutics, 2021
Advanced in vitro systems often combine a mechanical-physical instrument with a biological component e.g. cell culture models. For testing of aerosols, it is of advantage to consider aerosol behavior, particle deposition and lung region specific cell lines.
Daniel, Primavessy   +5 more
openaire   +2 more sources

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