Results 121 to 130 of about 5,350,274 (343)

City of sanctuary: Exploring multispecies democracy in a post-growth food future

open access: yesJournal of Political Ecology
This article grapples with two pressing problems endemic to capitalist agriculture: the exploitation of nonhuman animals and the enclosure of the agricultural commons.
Taylor Steelman
doaj   +2 more sources

Five minutes with Marianne Thieme: “We need to refocus our priorities instead of putting mankind at the centre of the universe” [PDF]

open access: yes, 2013
In 2006, the Party for the Animals (Partij voor de Dieren) became the first animal rights party to gain representation in a national parliament when it gained two seats in the House of Representatives of the Netherlands.
Thieme, Marianne
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Is it morally permissible to eat meat? [PDF]

open access: yes
Many approaches have been taken regarding this topic, some of them are anthropological or scientific that pursue the understanding of why we eat meat, but from the philosophical lens this question is solved in the field of applied ethics, which is the ...
Diez De Fex, Ana Maria
core  

Europe should embrace a cosmopolitan approach to animal rights [PDF]

open access: yes, 2015
The issue of animal welfare has become increasingly prominent across Europe in recent decades, with several animal rights parties now competing in European elections – most notably in the Netherlands where the Party for the Animals (PvdD) is currently ...
Cooke, Steve
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Neo-republicanism as a route to animal non-domination [PDF]

open access: yes, 2016
In this article, we reinterpret the current political turn in animal rights theory in terms of republican as opposed to liberal political theory. By appealing to the values of liberty and fraternity as well as equality, we argue for a conception of ...
Allen, Michael P., Von Essen, Erica
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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