Results 131 to 140 of about 5,350,274 (343)
On the Development of an Ethical Demand Theory [PDF]
As an increasing number of consumers shift to demand products on the basis on production practices, animal welfare protocols, human rights initiatives, it is becoming important that we develop new tools for evaluating the decision-making frameworks in ...
Amanor-Boadu, Vincent
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Canines in the Classroom: Service Animals in Primary and Secondary Educational Institutions [PDF]
, 2011 This Article focuses on the issue of whether a child with a disability has the legal right to attend a primary or secondary school with a service animal.
Huss, Rebecca J.
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
RelationsThe white-elitist veganism of the Global North does not adequately respond to the territorial, cultural, and economic particularities of the Latin American region.
Juan José Ponce León
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
ANIMAL ISSUES IN THE POLITICAL AND LEGAL SPHERE IN RUSSIA AND ABROAD
Правовое государство: теория и практикаIn Russia, the issue of the status of animals is at a medieval level, and it is extremely difficult to resolve it without ethical reflection. The purpose of the article is to consider a current problem concerning the status of animals.
BEZNOSOVA Yana Viktorovna +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A Philosophical Approach to Animal Rights and Welfare in the Tourism Sector
Journal of Tourism, Leisure and Hospitality, 2019 Although studies on animal rights and welfare in the field of tourism have begun to emerge in recent years, the subject is still new. In this context, a philosophical approach to animal rights and welfare in the tourism sector is put forward in this ...
Günlü Küçükaltan, Ebru +1 more
doaj
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source