Results 151 to 160 of about 5,350,274 (343)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

PROPERTY RIGHTS, GRAZING PERMITS, AND RANCHER WELFARE [PDF]

open access: yes
This study attempts to link factors affecting the demand for Bureau of Land Management grazing to perceived changes in permittee welfare over the 1962-92 period. Annual demand for federal forage is found to be sensitive to active preference, beef cow and
Lambert, David K.   +1 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The Rights of Animals: A Very Short Primer [PDF]

open access: yes, 2014
Do animals have rights? Almost everyone believes in animal rights, at least in some minimal sense; the real question is what that phrase actually means.
Sunstein, Cass Robert
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Raízes da resistência humana aos direitos dos animais: Bloqueios psicológicos e conceituais [PDF]

open access: yes, 2007
A combined psychological-epistemological study of the human blocks that stand in the way of the recognition of non-human animal sentience and legal rights.
Bartlett, Steven James
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

POLITICS AND MARKETS IN THE ARTICULATION OF PREFERENCES FOR ATTRIBUTES OF THE RAPIDLY CHANGING FOOD AND AGRICULTURAL SECTORS: FRAMING THE ISSUES [PDF]

open access: yes
Industrialization of the food and agricultural sectors changes the pattern of external effects. Participants helped or harmed in the process attempt to influence outcomes through markets and politics.
Abdalla, Charles W., Shaffer, James D.
core   +1 more source

Home - About - Disclaimer - Privacy