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Mycobacterium bovis Infection in Red Foxes in Four Animal Tuberculosis Endemic Areas in France [PDF]

open access: yesMicroorganisms, 2020
In France, animal tuberculosis (TB) due to Mycobacterium bovis (M. bovis) affects a multi-host community that include cattle and wildlife species such as wild boars (Sus scrofa), badgers (Meles meles), or wild deer (Cervus elaphus, Capreolus capreolus ...
Céline Richomme   +6 more
doaj   +2 more sources

Laboratory Diagnosis of Animal Tuberculosis in Tracing Interspecies Transmission of Mycobacterium bovis [PDF]

open access: yesPathogens
Mycobacterium is one of the most dangerous pathogens of both animals and humans. Bovine tuberculosis (BTB) is a disease caused by mycobacteria belonging to the Mycobacterium tuberculosis complex (MTBC), which spreads mainly among domestic cattle but also
Ewelina Szacawa   +6 more
doaj   +2 more sources

Protection and diagnostic interference induced by heat-inactivated, phage-inactivated and live vaccine prototypes against animal tuberculosis [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionVaccination emerges as a promising cost-effective tool to reduce the impact and spread of animal tuberculosis, especially in regions where test-and-slaughter eradication strategy is socioeconomically unfeasible or unfruitful for different ...
Leire Fernández-Veiga   +14 more
doaj   +2 more sources

Will we ever eradicate animal tuberculosis? [PDF]

open access: yesIrish Veterinary Journal, 2023
Two characteristics of the Mycobacterium tuberculosis complex (MTC) are particularly relevant for tuberculosis (TB) epidemiology and control, namely the ability of this group of pathogens to survive in the environment and thereby facilitate indirect ...
Christian Gortázar   +3 more
doaj   +2 more sources

Development and Challenges in Animal Tuberculosis Vaccination. [PDF]

open access: yesPathogens, 2020
Vaccination with Bacillus Calmette–Guérin (BCG) constituted a major advance in the prevention of human tuberculosis (TB) in the beginning of the past century. BCG has also a clear potential for use in animals and, in particular, in the main domestic species subjected to TB control programs, cattle.
Balseiro A   +3 more
europepmc   +7 more sources

Animal models of tuberculosis [PDF]

open access: yesEuropean Journal of Immunology, 2009
AbstractThere is a wide range of animal models of tuberculosis; which is fortunate, given that there is a wide range of complex biological phenomena to model. Nonetheless, the inadequacy of animal models is a chronic grievance amongst researchers, often expressed in the conclusion that the mouse is not a good model of human tuberculosis.
exaly   +3 more sources

Comparative pathology of experimental pulmonary tuberculosis in animal models

open access: yesFrontiers in Veterinary Science, 2023
Research in human tuberculosis (TB) is limited by the availability of human tissues from patients, which is often altered by therapy and treatment. Thus, the use of animal models is a key tool in increasing our understanding of the pathogenesis, disease ...
Laura Hunter   +7 more
doaj   +3 more sources

Impact of imperfect test sensitivity on determining risk factors : the case of bovine tuberculosis [PDF]

open access: yes, 2012
Background Imperfect diagnostic testing reduces the power to detect significant predictors in classical cross-sectional studies. Assuming that the misclassification in diagnosis is random this can be dealt with by increasing the sample size of a study ...
Camille Szmaragd   +4 more
core   +20 more sources

Whole Genome Sequencing Refines Knowledge on the Population Structure of Mycobacterium bovis from a Multi-Host Tuberculosis System

open access: yesMicroorganisms, 2021
Classical molecular analyses of Mycobacterium bovis based on spoligotyping and Variable Number Tandem Repeat (MIRU-VNTR) brought the first insights into the epidemiology of animal tuberculosis (TB) in Portugal, showing high genotypic diversity of ...
Ana C. Reis   +6 more
doaj   +1 more source

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