Results 131 to 140 of about 288,268 (315)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Welfare of Cattle kept for Beef Production

open access: yes, 2001
Content: 1) Introduction 2) State of the Industry 3) Hosing Systems 4) Behaviour of Cattle 5)Effect of Housing on the Welfare of the Animals 6) the effects of Management on Cattle Welfare 7)Futere Research Needed 8) Conclusions 9 ...
Scientific Committee on Animal Health and Animal Welfare
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Pacing polar bears and stoical sheep: testing ecological and evolutionary hypotheses about animal welfare.

open access: yes, 2004
Responses to potential threats to welfare vary greatly between species. Even closely related animals often differ in their fear of humans and/or novelty; their behavioural responses to pain; and when captive, their overall welfare and the form and ...
Mason, G.J., Clubb, R.
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Assessing and Improving Animal Welfare Using Applied Ethology

open access: yes
The papers in this Special Issue, entitled “Editorial Board Members’ Collection Series: Behaviour, Applied Ethology and Welfare of Farmed Animals”, bring to the forefront empirical data and theoretical discussions that contribute to the
Emma Fàbrega, Maria J. Hötzel
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

The Royal Zoological Society of Scotland’s Approach to Assessing and Promoting Animal Welfare in Collaboration with Universities [PDF]

open access: yes
Good zoos have four aims—to conserve species, educate the public, engage in research, and provide recreation—all of which can only be achieved when underpinned by high animal welfare standards.
Buchanan-Smith, Hannah M.   +9 more
core   +1 more source

Nutrition and animal welfare [PDF]

open access: yes, 2006
Ritskes-Hoitinga, Merel, Strubbe, Jan H.
openaire   +3 more sources

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