Results 111 to 120 of about 2,294,578 (257)

Beyond Glucocorticoids: Integrating Dehydroepiandrosterone (DHEA) into Animal Welfare Research

open access: yes, 2020
Animal welfare researchers are committed to identifying novel measures for enhancing the quality of life of individual animals. Recently, welfare scientists have emphasized the need for tracking multiple indicators of an animal’s behavioral ...
Jocelyn L. Bryant   +2 more
core   +1 more source

Scientific Opinion on the welfare of cattle kept for beef production and the welfare in intensive calf farming systems

open access: yesEFSA Journal, 2012
Information given in previous Opinions “Welfare of cattle kept for beef production” (SCAHAW, 2001) and “The risks of poor welfare in intensive calf farming systems” (EFSA, 2006) is updated and recent scientific evidence on the topics reviewed.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Guidance on Good Practice in Conducting Scientific Assessments in Animal Health using Modelling

open access: yesEFSA Journal, 2009
The European Food Safety Authority (EFSA) asked the Panel on Animal Health and Welfare to develop a guidance document on Good Practice in Conducting Scientific Assessments in animal health using modelling.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Scientific Opinion on Hatchery Waste as animal by‐products

open access: yesEFSA Journal, 2011
The risk posed by the possible use of dead‐in‐shell chicks for the production of processed petfood was assessed. According to current legislation two processing methods were considered i) treatment to a minimum Fc value of 3; and ii) treatment of at ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Farm Animal Welfare and Quality Verification [PDF]

open access: yes
Existing empirical evidence suggests that farm animal welfare may not be a top-of-mind issue for many consumers in North America. Nevertheless, there is pressure from animal welfare groups on food retailers and processors to implement more stringent ...
Uzea, Adrian D., Hobbs, Jill E.
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

State of the Animal: monitoring animal welfare and health in The Netherlands (0-measurement) : summary, full report is available in Dutch (report 323) [PDF]

open access: yes, 2010
25 measuring points summarise the results of policy measures for animal welfare and health in The ...
Ipema, A.H.   +7 more
core  

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