Results 121 to 130 of about 289,622 (315)

A systematic review of the potential uses of on-animal sensors to monitor the welfare of sheep evaluated using the Five Domains Model as a framework [PDF]

open access: yes, 2019
Fogarty, ES ORCiD: 0000-0003-0212-0156This systematic review explores the use of on-animal sensors in sheep and their potential application in objective welfare monitoring.
GM Cronin (9855005)   +11 more
core   +1 more source

Scientific Opinion on the welfare of cattle kept for beef production and the welfare in intensive calf farming systems

open access: yesEFSA Journal, 2012
Information given in previous Opinions “Welfare of cattle kept for beef production” (SCAHAW, 2001) and “The risks of poor welfare in intensive calf farming systems” (EFSA, 2006) is updated and recent scientific evidence on the topics reviewed.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Naturalness and Animal Welfare [PDF]

open access: yesAnimals, 2018
Naturalness is considered important for animals, and is one criterion for assessing how we care for them. However, it is a vague and ambiguous term, which needs definition and assessments suitable for scientific and ethical questions. This paper makes a start on that aim.
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Guidance on Good Practice in Conducting Scientific Assessments in Animal Health using Modelling

open access: yesEFSA Journal, 2009
The European Food Safety Authority (EFSA) asked the Panel on Animal Health and Welfare to develop a guidance document on Good Practice in Conducting Scientific Assessments in animal health using modelling.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Scientific Opinion on Hatchery Waste as animal by‐products

open access: yesEFSA Journal, 2011
The risk posed by the possible use of dead‐in‐shell chicks for the production of processed petfood was assessed. According to current legislation two processing methods were considered i) treatment to a minimum Fc value of 3; and ii) treatment of at ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Pet Ownership and Its Influence on Animal Welfare Attitudes and Consumption Intentions Among Chinese University Students [PDF]

open access: yes
As global awareness of animal welfare continues to rise, it has become essential to understand the factors that shape individual attitudes and consumption behaviors related to animal welfare.
Yongkun Yang   +4 more
core   +1 more source

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