Results 101 to 110 of about 2,418,274 (309)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Focusing on animal welfare [PDF]

open access: yesVeterinary Record, 2020
It is a fundamental irony that the UK proclaims to be a nation of animal lovers, yet tolerates an unacceptable amount of animal harm either wilfully or through ignorance. Three years ago the BVA published a list of all the key animal welfare problems in the UK.
openaire   +2 more sources

European approaches to ensure good animal welfare [PDF]

open access: yes, 2008
Conventions to protect domestic animals during transport, farming and slaughter were established by the Council of Europe and approved by many European states.
Bock, B.B.   +13 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Scientific Opinion on the electrical requirements for waterbath stunning equipment applicable for poultry

open access: yesEFSA Journal, 2012
The Commission requested that EFSA review relevant new scientific references on electrical stunning of poultry and to recommend, if necessary, new electrical requirements applicable for waterbath stunning equipment.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

At what extent does the study career influence the perception and attitude of university students towards the welfare of farmed animals?

open access: yes, 2017
Our study will investigate this aspect in university students belonging to two different MSc. degree courses (VM=Veterinary Medicine and SQAP=Safety and Quality in Animal Production) within the same Department (DIMEVET= Department of Veterinary Medical ...
Nannoni E.   +3 more
core   +1 more source

Chinese College Students’ Attitudes towards Animal Welfare

open access: yes, 2022
Understanding the attitude of stakeholders towards animals is critical for the development and improvement of animal welfare in a country. College students from veterinary, animal, and life sciences majors represent future key stakeholders that will ...
Ai Jingyi, Agathe Serres, Sara Platto
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A New, Practical Animal Welfare Assessment for Dairy Farmers

open access: yes, 2021
The Welfare Quality® assessment protocol (WQ) is the most extensive way to measure animal welfare. This study was set up to determine if resource-based welfare indicators, that are easier and faster to measure, could replace the more time consuming ...
Bert Snel   +4 more
core   +1 more source

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