Results 91 to 100 of about 2,294,578 (257)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Scientific Opinion on Review of the European Union Summary Report on trends and sources of zoonoses, zoonotic agents and food‐borne outbreaks in 2009 and 2010 specifically for the data related to bovine tuberculosis, Echinococcus, Q fever, brucellosis and non‐food borne diseases

EFSA Journal, 2012
Following a request from EFSA, the Animal Health and Welfare Panel delivered a scientific opinion reviewing the “European Union Summary Report on trends and sources of zoonoses, zoonotic agents and food‐borne outbreaks for 2009 and 2010“ specifically for
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Scientific Opinion on the use of animal‐based measures to assess welfare of dairy cows

EFSA Journal, 2012
Animal‐based measures, identified on the basis of scientific evidence, can be effectively used in the evaluation of the welfare of dairy cattle on farm in relation to laws, codes of practice, quality assurance schemes and management.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A systematic review of the potential uses of on-animal sensors to monitor the welfare of sheep evaluated using the Five Domains Model as a framework

, 2019
Fogarty, ES ORCiD: 0000-0003-0212-0156This systematic review explores the use of on-animal sensors in sheep and their potential application in objective welfare monitoring.
GM Cronin (9855005), Fogarty, Eloise S, Trotter, Mark G, David Swain (9838568), GM Cronin, DL Swain, Swain, David L, Eloise Fogarty (9796583), ES Fogarty, M Trotter, Cronin, GM, Mark Trotter (9841100)   +11 more
core   +1 more source

At what extent does the study career influence the perception and attitude of university students towards the welfare of farmed animals?

, 2017
Our study will investigate this aspect in university students belonging to two different MSc. degree courses (VM=Veterinary Medicine and SQAP=Safety and Quality in Animal Production) within the same Department (DIMEVET= Department of Veterinary Medical ...
Nannoni E., Di Pasquale J., Sardi L., Martelli G.   +3 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Private Animal Welfare Standards—Opportunities and Risks

, 2018
Simple Summary: In all European countries, farmers keeping animals must comply with European and national animal welfare legislation. Each government has a responsibility to make sure that the legislation is complied with by the farmers.
Charlotte Berg, Frida Lundmark, Helena Röcklinsberg, Lundmark Hedman, Frida,, Lundmark, Frida,, Röcklinsberg, Helena,, Sveriges lantbruksuniversitet., Berg, Lotta,   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source