Results 81 to 90 of about 2,294,578 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Annual report Animal Welfare Advisory Committee
, 2001 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).Northern Territory GovernmentThe Animal Welfare Act came into effect in March 2000 replacing the former Prevention of Cruelty to Animals Act.
core
EFSA Journal, 2013 This guidance defines the assessment process and the criteria that will be applied by the Animal Health and Welfare Panel to studies on known new or modified legal stunning interventions to determine their suitability for further assessment. The criteria
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Beyond the Five Freedoms: Animal Welfare at Modern Zoological Facilities
, 2023 The current manuscript highlights the aspects of an animal welfare program for a modern zoological facility. The program should be proactive to identify areas for continuous improvement as well as reactive to address any identified animal welfare ...
Sathya K. Chinnadurai, Lance J. Miller
core +1 more source
EFSA Journal, 2015 Since entering the eastern EU at the start of 2014, African swine fever (ASF) has spread locally in the wild boar population, independently of outbreaks in domestic pigs.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Farm membership of voluntary welfare schemes results in better compliance with animal welfare legislation in Great Britain [PDF]
, 2016 The Action Plan of the European Commission 2006 – 2010 proposed a move towards more private and less state regulation of animal welfare and Great British governments made a commitment to reduce the burden of inspection of farms by targeting high-risk ...
Clark, Corinna C. A. +4 more
core +1 more source
EFSA Journal, 2012 The Commission requested that EFSA review relevant new scientific references on electrical stunning of poultry and to recommend, if necessary, new electrical requirements applicable for waterbath stunning equipment.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source