Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Scientific Opinion on monitoring procedures at slaughterhouses for pigs
This scientific opinion proposes toolboxes of welfare indicators for developing monitoring procedures at slaughterhouses for pigs stunned with the head‐only electrical method or carbon dioxide at high concentration.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Scientific Opinion on monitoring procedures at slaughterhouses for sheep and goats
This scientific opinion proposes toolboxes of welfare indicators for developing monitoring procedures at slaughterhouses for sheep and goats stunned with the head‐only electrical method or slaughtered without stunning. In particular, the opinion proposes
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Scientific Opinion on electrical requirements for poultry waterbath stunning equipment [PDF]
The European Commission (EC) requested that the EFSA Panel on Animal Health and Welfare (AHAW Panel) delivers a scientific opinion on a study that proposes parameters for poultry electrical waterbath stunning different to those laid down in Council ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Statement on the use of animal‐based measures to assess the welfare of animals
The overall aim of the work outlined in this statement is to help establish a common framework for future scientific opinions dealing with the use of animal‐based measures to assess the welfare of animals.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Scientific Opinion on the Role of Tick Vectors in the Epidemiology of Crimean-Congo Hemorrhagic Fever and African Swine Fever in Eurasia [PDF]
The report provides an update on the role of the tick vectors in the epidemiology of African swine fever (ASF) and Crimean and Congo haemorrhagic fever (CCHF) in Eurasia, specifically to review of the geographical distribution of the relevant ticks with ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
Scientific Opinion on Geographic Distribution of Tick-borne Infections and their Vectors in Europe and the other Regions of the Mediterranean Basin [PDF]
This report is the second of a series of two technical assessments of the role of ticks in transmission of animal diseases and zoonoses in Eurasia. A previous published scientific opinion (EFSA Journal 2010; (8)8, 1703) focused on two diseases- Crimean ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj +1 more source