Results 81 to 90 of about 747,053 (355)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Animal welfare in a global perspective [PDF]

open access: yes, 2009
Global survey of animal-welfare regulations, practices and perceptions, with case studies on poultry meat from Brazil and Thailand, eggs from India and the USA, welfare regulations of farmed fish and welfare aspects related to (perceived) overpopulation ...
Bracke, M.B.M.
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Blue whales and seismic surveying in Australia [PDF]

open access: yes
Blue whale populations were devastated in the last century by commercial whaling, which reduced blue whales from a quarter of a million to just a few hundred animals. Australian waters are home to both the Antarctic blue whale and a smaller sub- species,
International Fund for Animal Welfare (IFAW)
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Planning for better animal health and welfare, Report from the 1st ANIPLAN project workshop, Hellevad, October 2007 [PDF]

open access: yes, 2008
’Minimising medicine use in organic dairy herds through animal health and welfare planning’, ANIPLAN, is a CORE-Organic project which was initiated in June 2007.
Atkinson, Chris   +15 more
core  

Ethics, space, and somatic sensibilities: comparing relationships between scientific researchers and their human and animal experimental subjects [PDF]

open access: yes, 2011
Drawing on geographies of affect and nature-society relations, we propose a radical rethinking of how scientists, social scientists, and regulatory agencies conceptualise human and animal participants in scientif ic research. The scientific rationale for
Birke L   +33 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Enzootic bovine leukosis

open access: yesEFSA Journal, 2015
Enzootic bovine leukosis is a disease of cattle caused by bovine leukemia virus (BLV). The virus causes a persistent, life‐long infection in a subset of B cells.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

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