Results 101 to 110 of about 15,188 (291)

La chèvre ou la femme. Parentés de lait entre animaux et humains au Moyen Âge.

open access: yesImages Re-Vues, 2012
This article launches an investigation about images of interspecies breast-feeding in the Middle Ages. Thought as a transmission of humors and features, milk kinship was higlhy rated at the time, and was often questioned about fostering practices. Breast-
Pierre-Olivier Dittmar   +2 more
doaj   +1 more source

Performing expertise in human–animal relationships: performative instability and the role of counterperformance [PDF]

open access: yes, 2015
This paper explores how the human–animal relationship is used to inform the construction of expertise about how best to manage relationships with animals.
Franklin, Alex, Schuurman, N.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The (In)Human Condition

open access: yesSillages Critiques, 2016
The article examines Simon Stephens's seminal play Three Kingdoms (2012), a defining moment in his enduring working relationship with director Sebastian Nübling and a decidedly internationalist staging effort that enabled cross-collaboration between ...
Vicky Angelaki
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Canine Actors and Melodramatic Effects: The Dog of Montargis Arrives on the English Stage

open access: yesCahiers Victoriens et Edouardiens, 2017
This work examines how, through the adaptation of the widely celebrated French canine melodrama Le chien de Montargis onto the British stage, Victorian society explored and attempted to define its own distinct cultural alliance and conceptualization of ...
Claudia Alonso Recarte
doaj   +1 more source

Lab‐Grown Meat and Veganism: A Virtue‐Oriented Perspective [PDF]

open access: yes, 2019
The project of growing meat artificially represents for some the next best thing to humanity. If successful, it could be the solution to several problems, such as feed- ing a growing global population while reducing the environmental impact of raising ...
Alvaro, Carlo
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Music and the Mind [PDF]

open access: yes, 2016
How does music affect a work of literature?
Densmoor, Amanda K.
core   +1 more source

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