Results 11 to 20 of about 164,967 (257)

Cutaneous melanoma in genetically modified animals [PDF]

Pigment Cell Research, 2007
AbstractCutaneous melanomas are tumors originating from skin melanocytes which are present in hair follicles, and interfollicular epidermal and dermal layers. Experimental work in model systems involves in silico, in vitro and in vivo analyses. Such models allow to mimick melanocytic aberrations characteristic of melanoma, and to potentially exploit ...
Lionel, Larue, Friedrich, Beermann
openaire   +2 more sources

Effects of Genetically Modified Food on Gut Microbiota in Animal Models: A Systematic Review [PDF]

Journal of Health Sciences and Surveillance System
Background: There are some debates about the possible unintended effects of genetically modified (GM) crops on consumer health. The gut microbiota plays an important role in maintaining the health of the host, especially in gastrointestinal diseases. The
Maryam Nejabat, Mohammadreza Heydari, Parisa Keshani, Hassan Joulaei, Nazanin Nazari   +4 more
doaj   +1 more source

Modern approaches to production of safe and effective genetically modified rabies vaccines for animals

Ветеринария сегодня, 2023
Rabies is a dangerous zoonoticdisease that affects the central nervous system, causes encephalomyelitis and paralyses and Is almost invariably fatal.
M. I. Doronin, A. Mazloum, D. V. Mikhalishin, M. N. Mitrofanova, A. Yu. Sukharkov, V. V. Kiseleva, A. V. Sprygin   +6 more
doaj   +1 more source

Factors Affecting the Adoption of Genetically Modified Animals in the Food and Pharmaceutical Chains

Bio-based and Applied Economics, 2012
The production of genetically modified (GM) animals is an emerging technique that could potentially impact the livestock and pharmaceutical industries.
Cristina Mora, Davide Menozzi, Gijs Kleter, Lusine H. Aramyan, Natasha I. Valeeva, Karin l. Zimmermann, Giddalury Pakki Reddy   +6 more
doaj   +1 more source

Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

Animals, 2021
In the EU, the breeding of genetically modified laboratory animals is, by definition, an animal experiment if the offspring may experience pain, suffering, or harm. In order to determine the actual burden of genetically modified mice, established methods
Thomas Kammertoens, Sarah Jeuthe, Heike Baranzke, Antonina Klippert, Christa Thöne-Reineke   +4 more
doaj   +1 more source

Effects of Feeding Genetically Modified Crops to Domestic Animals: A Review

Turkish Journal of Agriculture: Food Science and Technology, 2019
Genetically modified (GM) crops are being planted at large scale worldwide. In most of the countries, GM crops are processed into livestock feed. The land is used for cultivation of GM plants has been increased in recent years; in 2012 GM plants were ...
Muhammad Zeeshan Akram, Sema Yaman, Hassan Jalal, Sibel Canoğulları Doğan, Sana Shahid, Basit Shaukat Ali   +5 more
doaj   +1 more source

Manipulations with early mouse embryos for generation of genetically modified animals

Вавиловский журнал генетики и селекции, 2017
Recently, genome-editing technologies have  become more efficient and accessible. The discovery of nucleases for directional genome editing (CRISPR/Cas9, TALEN, ZFNs) significantly accelerated and simplified the production of mice with targeted gene ...
A. N. Korablev, I. A. Serova, B. V. Skryabin   +2 more
doaj   +1 more source

Degeneration of Bioprosthetic Heart Valves: Update 2020

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment of choice in patients requiring heart valve replacement surgery.
Alexander E. Kostyunin, Arseniy E. Yuzhalin, Maria A. Rezvova, Evgeniy A. Ovcharenko, Tatiana V. Glushkova, Anton G. Kutikhin   +5 more
doaj   +1 more source

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys. [PDF]

PLoS ONE, 2016
The present study was performed to evaluate the food safety of TT51-1, a new type of genetically modified rice that expresses the Cry1Ab/Ac protein (Bt toxin) and is highly resistant to most lepidopteran pests.
Xiaoyan Tan, Xiaobing Zhou, Yao Tang, Jianjun Lv, Lin Zhang, Li Sun, Yanwei Yang, Yufa Miao, Hua Jiang, Gaofeng Chen, Zhiying Huang, Xue Wang   +11 more
doaj   +1 more source

Danos oxidativos e neurodegeneração: o quê aprendemos com animais transgênicos e nocautes?

Química Nova, 2006
Accumulated evidence indicates that oxidative stress plays a role in neurodegenerative diseases, such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis.
Lívea Fujita Barbosa, Marisa H.G. de Medeiros, Ohara Augusto   +2 more
doaj   +1 more source