Results 191 to 200 of about 485,436 (276)

Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride produced with <i>Corynebacterium glutamicum</i>CGMCC 7.453 for all animal species (Eppen Europa SAS). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Anguita M, Cionci NB, Innocenti ML, Kolona M, Tarrés-Call J.   +21 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

From mother to piglet: the lasting influence of the maternal microbiome. [PDF]

Anim Microbiome
Tancredi A, Matthijs T, Cox E, Van Immerseel F, Goossens E.   +4 more
europepmc   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Safety evaluation of the food enzyme β-galactosidase from the non-genetically modified <i>Kluyveromyces lactis</i> strain LAC-01. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Lunardi S, Andryszkiewicz M, Marini E, Liu Y.   +17 more
europepmc   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

Revisiting the role of Substance P and CGRPα. [PDF]

Elife
Cai W, Khoutorsky A.
europepmc   +1 more source

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

Advanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie, Jingyi Ju, Zhenxing Wang, Jun Chen, Lin‐Ping Wu, Jiaming Sun   +5 more
wiley   +1 more source

Early Results of an Infant Model of Orthotopic Cardiac Xenotransplantation. [PDF]

J Heart Lung Transplant
Mitchell CB, Simmons J, Hodo CL, Neal SJ, Chitta S, Vo C, Bakshi K, Juliani J, Fenske J, Cleveland DC, Cleveland JD.   +10 more
europepmc   +1 more source

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source