Results 201 to 210 of about 7,438,473 (359)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Behavioral Convergence with Physiological Divergence: Sex Differences in Hormones but Not Social Behavior in Beagle Dogs. [PDF]

Animals (Basel)
Xiao YH, Zhao ZH, Jiang XY, Zhang J, He WB, Dong R, Zhang XT, Tao LX, Ma JL, Li JX, Zhang YP.   +10 more
europepmc   +1 more source

Recognition and Alleviation of Distress in Laboratory Animals

, 2008

core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Brucellosis Surveillance - United States, 2010-2024. [PDF]

MMWR Surveill Summ
Locke NS, DeBord KM, Tiller RV, Stoddard RA, Saile E, Kraushaar V, Adame G, Austin C, Ackelsberg J, Newman A, Kharod G, Guerra M, Traxler RM, Parrado M, Bower WA, Cossaboom CM, Blackburn D, Hoffmaster AR, Weiner Z, Negron ME.   +19 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The Effect of Zinc Gluconate Supplementation on the Intestinal Microbiota and Growth Performance of Yorkshire Pigs. [PDF]

Animals (Basel)
Zhu Y, Lu J, Fan J, Shen L, Zhu L, Tan Y, Liu Y, Gan M.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Effects of Clicker Training on Behavioral and Stress Markers of Welfare in the F1 Generation of CD1 Mice: A Pilot Study. [PDF]

Animals (Basel)
Reichel S, Gonzalez-Uarquin F, Pichl D, Radyushkin K, Baumgart J, Baumgart N.   +5 more
europepmc   +1 more source

Side effects of selection in laboratory animals

Genetics Selection Evolution, 1978
Roberts RC
doaj   +1 more source