Results 131 to 140 of about 3,256,140 (321)

Reoxygenation of asphyxiated newborn piglets: administration of 100% oxygen causes significantly higher apoptosis in cortical neurons, as compared to 21%. [PDF]

open access: yes, 2014
Di Felice E   +11 more
core   +1 more source

Universal Mortality Law, Life Expectancy and Immortality

open access: yes, 2004
Well protected human and laboratory animal populations with abundant resources are evolutionary unprecedented, and their survival far beyond reproductive age may be a byproduct rather than tool of evolution.
Arantes-Oliveira   +24 more
core   +1 more source

A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

open access: yesAdvanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang   +14 more
wiley   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Molecular Biology at the bedside: the impact of Genomics on the practice of medicine [PDF]

open access: yes, 2002
Imagine being a newborn baby, discharged home after delivery, with a most unusual gift, a compact disc (CD) carrying all data on "My Genome". The parents would be most anxious to play it on their home PC. Soon, they could discover whether their child has
Felice, Alex
core  

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Is L-carnitine protective in hypoxic cerebral edema in newborn mice?

open access: yesThe Turkish Journal of Pediatrics, 1993
The value of carnitine in the prevention of cerebral edema due to acute severe hypoxia in 38 newborn mice was studied. Twenty-nine animals received normal saline (0.25 ml) or carnitine (16 mmol/kg) intraperitoneally, thirty minutes before exposure
M Yurdakök, R Haziroğlu, T Coşkun
doaj  

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

open access: yesAdvanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang   +9 more
wiley   +1 more source

Evaluation of propylthiouracil effect on rat,s ovarian activity [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 1997
this study  Evaluation the physiological activity effects of thyroid glands on the process of development and growth of ovaries and reproductive organs in rats.the study also investigates the adverse effects of antithyroid compounds adminidtered to ...
H.R Sadeghipour-Rasooli, M Ramezani
doaj  

A Comprehensive Review of Bovine Colostrum Components and Selected Aspects Regarding Their Impact on Neonatal Calf Physiology

open access: yesAnimals
Simple Summary Colostrum is the “starter kit” for every calf, containing nutrients, bioactive components, cells, and microorganisms that provide energy and protection against pathogens and contribute to the maturation and development of the ...
Flávio G. Silva   +4 more
semanticscholar   +1 more source

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