Results 131 to 140 of about 244,970 (309)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Identification of de‑epithelized structures of pig placenta

Siberian Journal of Life Sciences and Agriculture
The article presents the structural features of dе-epithelized structures in the placenta of sows. A systematic histological examination of placentas in pregnant animals allowed us to identify new methods for assessing their condition, taking into ...
Alexander V. Agarkov, Nikolay V. Agarkov, Roman A. Tsyganskiy, Nikolay V. Belugin, Natalia A. Pisarenko   +4 more
doaj   +1 more source

Developmental adaptations to gravity in animals [PDF]

Terrestrial animals have adapted to a constant gravitational stress over millions of years. Tissues of the cardiovascular system and lumbar spine in tall species of animals such as the giraffe are particularly well adapted to high and variable vectors of
Hargens, Alan R.
core   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

STATUTUL IMUN AL PURCEILOR OBŢINUŢI DE LA SCROAFE CU ADMINISTRAREA REMEDIULUI ,,ASTATUTUL IMUN AL PURCEILOR OBŢINUŢI DE LA SCROAFE CU ADMINISTRAREA REMEDIULUI ,,APIFITOSTIMULINĂ” ÎN PERIOADA POSTNATALĂ TIMPUPIFITOSTIMULINĂ” ÎN PERIOADA POSTNATALĂ TIMPURIE

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2010
The administration of „Apifitostimulin” in gestating sows led to increase of the immunobiological status of newborn pigs. At the 3rd day of their life the increase of immunoglobulins IgA, IgG, IgM and T-Lymphocytes in serum was registered to compare ...
USM ADMIN
doaj  

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Astrovirus infection in animals (literature review)

Ветеринария сегодня
Viral agents are a major cause of mass gastroenteritides in newborn calves in the countries around the world. Early postnatal diarrhea as the main reason of morbidity and mortality in young animals leads to serious problems in the commercial livestock ...
V. A. Mischenko, A. V. Mischenko, Т. B. Nikeshina, О. N. Petrova   +3 more
doaj   +1 more source

Cattle Trade and the Risk of Importing Animal Diseases into the Netherlands [PDF]

Projections of live cattle trade in the EU-25 assist to reduce the uncertainty on the risk of importing animal diseases in the Netherlands. The accession of 10 member states to the European Union has a potentially large impact on livestock trade in the ...
Achterbosch, Thom J., Dopfer, Dorte D.V., Tabeau, Andrzej A.   +2 more
core   +1 more source

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

Advanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin, Karthikeyan Narayanan, Deepak Vashishth   +2 more
wiley   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source