Results 61 to 70 of about 130,526 (267)
Advanced Healthcare Materials, EarlyView.A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee +3 more
wiley +1 more source
Functional recruitment of newborn hippocampal neurons after experimental stroke
Neurobiology of Disease, 2012 The adult brain responds to diverse pathologies such as stroke with increased generation of neurons in the dentate gyrus of the hippocampus. However, only little is known regarding the functional integration of newborn neurons into pre-existing neuronal ...
Christiane S. Geibig +2 more
doaj +1 more source
Protection of Newborn Animals through Maternal Immunization
Journal of Comparative Pathology, 2007 Providing protective immunity to neonatal animals in early life is associated with numerous challenges regarding vaccine safety and efficacy. A much simpler approach is maternal vaccination, either before or during pregnancy, to provide the neonate with passively transferred immunity.
Pravieux, J.J. +3 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Advanced Materials, EarlyView.Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib +10 more
wiley +1 more source
Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue
Advanced Materials Technologies, EarlyView.Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan +10 more
wiley +1 more source
Ветеринарная патология, 2012 The complex consist of an immunomodulator of T and B-activin, introduced newborn (3-7 days), affects the cellular and humoral immunity and natural resistance of the animals, improving the immune status of these animals from the four-teenth day, and up to
doaj
The Future of Research in Cognitive Robotics: Foundation Models or Developmental Cognitive Models?
Advanced Robotics Research, EarlyView.Research in cognitive robotics founded on principles of developmental psychology and enactive cognitive science would yield what we seek in autonomous robots: the ability to perceive its environment, learn from experience, anticipate the outcome of events, act to pursue goals, and adapt to changing circumstances without resorting to training with ...
David Vernon
wiley +1 more source
Pediatrics and Neonatology, 2014 Amplitude-integrated electroencephalogram (aEEG) is a simplified, alternative means of monitoring cerebral function and may be more useful clinically in some situations than conventional EEG.
Ji-Mei Wang +4 more
doaj +1 more source