A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Clinical trial results of an associated vaccine against cattle clostridiosis and escherichiosis [PDF]
In veterinary practice, gastrointestinal diseases of newborn calves, caused by the association of pathogenic bacteria, in particular Clostridium perfringens and Escherichia coli, are often observed.
Spiridonov Anton +9 more
doaj +1 more source
The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj +1 more source
STUDY PROTOCOL: Improving newborn survival in rural southern Tanzania: a cluster-randomised trial to evaluate the impact of a scaleable package of interventions at community level with health system strengthening [PDF]
Child mortality has declined substantially in many countries including Tanzania, but newborn mortality remains high and around 3 million babies die every year in the first 28 days of life.
Marchant, T +12 more
core +1 more source
Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Aggregative properties of red blood cells platelets in young cattle in the first 10 days of life
Objective: to establish features erythrocyte and platelet at healthy calfs in a phase newborn. The animals every day during the newborn phase determined aggregation cells using light microscopy and Visual mikrometod aggregation platelets. The results may
T A Belova +3 more
doaj
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
South American subterranean rodents are mainly described as solitary and mutual synchronization was never observed among individuals maintained together in laboratory.
Barbara Mizumo Tomotani +3 more
doaj +1 more source
Newborn screening for cystic fibrosis: evaluation of benefits and risks and recommendations for state newborn screening programs [PDF]
In November 2003, CDC and the Cystic Fibrosis Foundation cosponsored a workshop to review the benefits and risks associated with newborn screening for cystic fibrosis (CF).
Grosse, Scott D. +6 more
core
Pilot programs in newborn screening
The term "pilot study" has been used over the years to describe the evaluation of the many elements involved in deciding whether a proposed condition should be added to a newborn screening (NBS) panel, and until recently, was unilaterally used to ...
Sherwin, John +4 more
core +1 more source

