Results 101 to 110 of about 5,854,621 (365)
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Reducing antimicrobial use in food animals
Science, 2017 Consider user fees and regulatory caps on veterinary use The large and expanding use of antimicrobials in livestock, a consequence of growing global demand for animal protein, is of considerable concern in light of the threat of antimicrobial resistance (
T. V. Van Boeckel +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Mivart's the CatThe Cat. An Introduction to the Study of Backboned Animals, Especially Mammals.St. George Mivart [PDF]
, 1882 openalex +1 more source
Disconnexion syndromes in animals and man. I.
Brain : a journal of neurology, 1965 As I have pointed out earlier, when I met Oliver Zangwill in 1961 at a meeting on dyslexia in Baltimore, he listened patiently to the exposition of my ideas on the significance of the cortico-cortical connections for the higher functions.
N. Geschwind
semanticscholar +1 more source
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo
Pharmaceutical Biology, 2019 Context: Ursolic acid (UA; 3β-hydroxy-urs-12-en-28-oic acid), one of the pentacyclic triterpenoids found in various plants and herbs, possesses some beneficial effects under pathological conditions, including combating hepatic fibrosis.
Chang-Geng Xu +3 more
doaj +1 more source
Open Journal of Humanities, 2019 Description: The paper evolves from the consideration on the necessity of sensitizing students to a very actual topic such as animal Ethics and of stimulating empathy towards all the species of the planet.
Giannella Biddau
doaj +1 more source