Results 121 to 130 of about 9,215,153 (385)

Veterinary science : humans, animals and health [PDF]

, 2011
This living book is a collection of open access materials bringing scientific papers to a humanities ...
Fudge, Erica, Palmer, Clare
core  

Animals and Animals

Between the Species: An Online Journal for the Study of Philosophy and Animals, 2010
Speciesism is the wrong of not acknowledging the moral qualities that non-human animals possess that are similar or equivalent or even superior to the moral qualities that human beings possess. However, since it is manifestly clear that no one thinks that apes are in any way obligated to human beings, it clearly cannot be a form of speciesism to be ...
openaire   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Toying with Death in Walden

E-REA, 2017
This essay tries to question the usual, quasi-consensual reading of Walden as a celebration of life, health and youth. It relies on a network of underground metaphors which introduce a number of disturbing interferences into the text, from slumber ...
Yves CARLET
doaj   +1 more source

Political animals [PDF]

, 1986
In the last few years the animal rights movement has grown out of all recognition.
Mills, S, Williams, P
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

DIFFERENTIAL REINFORCEMENT OF ALTERNATIVE BEHAVIOR INCREASES RESISTANCE TO EXTINCTION: CLINICAL DEMONSTRATION, ANIMAL MODELING, AND CLINICAL TEST OF ONE SOLUTION [PDF]

, 2010
F. Charles Mace, Jennifer J. McComas, Benjamin C. Mauro, Patrick R. Progar, Bridget A. Taylor, Ruth A. Ervin, Amanda N. Zangrillo   +6 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Animal Metaphors and University Rape Culture: A Look at Violence against Women on Campuses in Canada, Spain, Australia, Mexico, and the USA

Feminismo/s
This article focuses on animal metaphors in real cases of rape culture in universities in the Anglophone and Hispanophone worlds. To this aim, it analyzes the animal metaphors permeating several episodes of violence against female students perpetrated on
Irene Lopez-Rodriguez
doaj   +1 more source