Results 121 to 130 of about 9,120,435 (385)

Preclinical Applications of Multi-Platform Imaging in Animal Models of Cancer [PDF]

open access: bronze, 2020
Natalie J. Serkova   +9 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Major and Minor Causes of Geophagy–Lithophagy in Animals and Humans

open access: yesGeosciences
The analyzed data set on the problem of geophagy–lithophagy shows that the instinctive desire, preserved in many groups of animals and humans, to eat mineral–crystalline substances—products of hypergenic transformation of various rocks in the most ...
Alexander M. Panichev   +1 more
doaj   +1 more source

Animals Among Us: The Lives of Humans and Animals in Contemporary American Fiction edited by John Yunker [PDF]

open access: yes, 2015
Review of Animals Among Us: The Lives of Humans and Animals in Contemporary American Fiction, edited by John ...
Reis, Ashley E.
core   +1 more source

Reducing antimicrobial use in food animals

open access: yesScience, 2017
Consider user fees and regulatory caps on veterinary use The large and expanding use of antimicrobials in livestock, a consequence of growing global demand for animal protein, is of considerable concern in light of the threat of antimicrobial resistance (
T. V. Van Boeckel   +8 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

After Ontology, After Essence: Recasting the ‘Human’ from within the Socio-Eco-Techno Interface

open access: yesAnglophonia, 2013
Les limites érigées entre l’humain et le non-humain et entre l’humain en tant qu’espèce et l’Humain en tant que catégorie morale ne permettent pas de comprendre l’humain comme chiasme.
S. Romi Mukherjee
doaj   +1 more source

Similarity or Difference as a Basis for Justice: Must Animals Be Like Humans to Be Legally Protected from Humans? [PDF]

open access: yes, 2007
Justice may not require that animals be exactly the same as humans or that they have rights exactly coterminous with the rights of humans, but justice would require that animals receive protection in ways that match up with those similarities they share ...
Bryant, Taimie L.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Toying with Death in Walden

open access: yesE-REA, 2017
This essay tries to question the usual, quasi-consensual reading of Walden as a celebration of life, health and youth. It relies on a network of underground metaphors which introduce a number of disturbing interferences into the text, from slumber ...
Yves CARLET
doaj   +1 more source

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