Results 151 to 160 of about 6,059,454 (285)

The role of postmortem microbiome knowledge in veterinary medicine

open access: yesRevSALUS, 2022
Pauline Ferrari   +8 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Pulmonary tuberculosis in animals from an anatomical point of view

open access: yesRevSALUS, 2022
Jessica Gaubert   +3 more
doaj   +1 more source

Animating through Animation

open access: yes, 2015
Research has found that young people not in education, employment or training (NEET) suffer disproportionately high levels of social adversities and are at greater risk of involvement in crime. Whilst policy-makers across many European jurisdictions have made NEET a focus for intervention, it is only very rarely that the voice of young people flows ...
openaire  

rTCT: Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration. [PDF]

open access: yesHippocampus
Duncan S   +13 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Sex-Dependent Effects of Angiotensin II and Calcineurin in the Vasculature of Mice. [PDF]

open access: yesActa Physiol (Oxf)
Nolze A   +6 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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