Results 181 to 190 of about 30,181 (241)
Animal Genetics, Volume 57, Issue 3, June 2026.ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Mohammad Mehdi Akbarin +6 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1286-1305, June 2026.ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld +9 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1306-1314, June 2026.ABSTRACT KBG syndrome is a rare autosomal dominant neurodevelopmental disorder caused by ANKRD11 haploinsufficiency and is characterized by short stature, distinctive facial features, intellectual disability or developmental delay, congenital anomalies and skeletal anomalies.
Marit van der Leij +5 more
wiley +1 more source
Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik +4 more
wiley +1 more source
Neuroprotective Peptide NAPVSIPQ Antagonizes Ethanol Inhibition of L1 Adhesion by Promoting the Dissociation of L1 and Ankyrin-G. [PDF]
Biol Psychiatry, 2020 Dou X, Lee JY, Charness ME.
europepmc +1 more source
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.Modulation of K2P and Kv7 channels has the potential to reduce hyperexcitability and hypersynchronicity within the thalamocortical system. This offers a new avenue to suppress spike and wave discharges, the electrophysiological hallmark of absence epilepsy.
Anushka Takhi +3 more
wiley +1 more source
Cancer, Volume 132, Issue S1, 1 June 2026.Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho +3 more
wiley +1 more source
[Effects of olfactory deprivation on action potential and ankyrin-G expression in glutamatergic neurons in the barrel cortex of mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2020 Ni H +5 more
europepmc +1 more source
Ecology and Evolution, Volume 16, Issue 6, June 2026.We re‐analysed RAD‐Seq data from brown trout using a conspecific reference genome and alternative SNP pipelines. Population structure was robust across methods, but using the brown trout reference improved detection of biologically relevant outlier SNPs. ABSTRACT Genome‐wide association studies with identification of biologically relevant genes rely on
Giovanna Mottola +4 more
wiley +1 more source
Localization of Ankyrin G, Nav and KCNQ1 channels to neuro-cardiac junctions
, 2019 Abstract Cardiac performance is regulated by input of sympathetic nervous system. Junctions between sympathetic ganglion neurons (SGN) and cardiac myocytes are unique cell-cell contacts designed for the efficient regulation of heart rate and contractility by the autonomic nervous system.
openaire +1 more source